Quick Links: Skip to main page content
Skip to Search
Skip to Topics Menu
Skip to Common Links
U.S. Food & Drug Administration
Follow FDA
En Español
Search FDA
Home
Food
Drugs
Medical Devices
Radiation-Emitting Products
Vaccines, Blood & Biologics
Animal & Veterinary
Cosmetics
Tobacco Products
PhishPharm - Detail
FDA Home
PhishPharm
Detail
-
Please note:
JavaScript must be enabled for this application to work properly.
Check your settings
if you are unsure if your JavaScript is enabled.
Title:
Comparative pharmacokinetics of oxytetracycline in rainbow trout (Salmo gairdneri) and African catfish (Clarias gariepinus).
Authors:
Grondel JL, Nouws JFM, Schutte AR, Driessens F
Drug:
Oxytetracycline
Fish species:
Catfish, North African
Date:
1989
t1/2-hr:
80
Sample:
blood, plasma
Ave Weight (gm):
293
Ave Water temp (°C):
25
Water:
Freshwater
Dosage:
60 mg/kg sd
Route:
IV
Comments:
AUC = 5369+/- 1102 ug h/ml. T 1/2 alpha = 5.2 h, beta 80.3. Cl, Vc, and Vd were calculated in a model-independent way according to Baggot (1977).
Cl:
0.0114 L/kg/h
Vc:
0.70+/-0.09 L/kg
Vd:
1.33+/-0.22 L/kg
Citation:
J. Veterinary Pharmacology and Therapeutics 12:157-162
Link:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=2746722
Genus Species:
Clarias gariepinus
Drug Class:
Antibiotic-Tetracycline
t1/2-detail:
80.3+/-3.9 h
Wt gm-detail:
293+/-45 g
Water temp (°C)-detail:
25 C
Dosage-detail:
60 mg/kg sd
Method:
Micro
Authors-red:
Grondel JL, Nouws JFM, Schutte AR, Driessens F
-
-