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U.S. Department of Health and Human Services

PhishPharm - Detail
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Title:  Pharmacokinetics of sulphadiazine and trimethoprim in carp (Cyprinus carpio L.) acclimated at two different temperatures.
 
Authors:  Nouws JFM, van Ginneken VJT, Grondel JL, Degen M
 
Drug:  Trimethoprim
 
Fish species:  Carp, common
 
Date:  1993
 
t1/2-hr:  41
 
Sample:  blood, plasma
 
Ave Weight (gm):  380
 
Ave Water temp (°C):  10
 
Water:  Freshwater
 
Dosage:  20 mg/kg sd
 
Route:  IV
 
Cl:  0.047+/-0.018 L/kg/h
 
Vd:  3.1+/-0.41 L/kg
 
Citation:  J. Veterinary Pharmacology and Therapeutics 16:110-113.
 
Link:  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=8478994&dopt=Abstract  Opens a new window
 
Genus Species:  Cyprinus carpio
 
Drug Class:  Antibiotic-Sulfa
 
t1/2-detail:  40.7+/-5.6 h
 
Wt gm-detail:  380+/-25g
 
Water temp (°C)-detail:  10C
 
Dosage-detail:  20 mg/kg sd
 
Method:  HPLC
 
Authors-red:  Nouws JFM, van Ginneken VJT, Grondel JL, Degen M
 
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