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U.S. Department of Health and Human Services

PhishPharm - Detail
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Title:  Pharmacokinetic and pharmacodynamic properties of Metomidate in turbot (Scophthalmus maximus) and halibut (Hippoglossus hippoglossus).
 
Authors:  Hansen MK, Nymoen U, Horsberg TE
 
Drug:  Metomidate
 
Fish species:  Halibut, Atlantic
 
Date:  2003
 
t1/2-hr:  6
 
Sample:  blood, plasma
 
Ave Weight (gm):  166
 
Ave Water temp (°C):  10
 
Water:  Brackish
 
Dosage:  3 mg/kg sd
 
Route:  IV
 
Comments:  Brackish water - salinity 3%
 
Cl:  0.099 L/kg/h
 
Vd:  0.21 L/kg
 
Citation:  J. Veterinary Pharmacology and Therapeutics 26:95-103
 
Link:  http://onlinelibrary.wiley.com/doi/10.1046/j.1365-2885.2003.00454.x/abstract  Opens a new window
 
Genus Species:  Hippoglossus hippoglossus
 
Drug Class:  Anesthetic-Metomidate
 
t1/2-detail:  5.8 h
 
Wt gm-detail:  166+/-47 g
 
Water temp (°C)-detail:  10.3+/-0.5 C
 
Dosage-detail:  3 mg/kg sd
 
Method:  HPLC
 
Authors-red:  Hansen MK, Nymoen U, Horsberg TE
 
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