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Title:
Pharmacokinetics of sulphadimethoxine and ormetoprim in a 5:1 ratio following intraperitoneal and oral administration, in the hybrid striped bass (Morone chrysops x Morone saxitalis).
Authors:
Bakal RS, Bai SA, Stoskopf MK
Drug:
Ormetoprim
Fish species:
Bass, striped (hybrid)
Date:
2004
t1/2-hr:
7
Sample:
blood, plasma
Ave Weight (gm):
685
Ave Water temp (°C):
17
Water:
Freshwater
Dosage:
50 mg/kg sd
Route:
IP
Comments:
Sulphadimethoxine and Ormetoprim in a 5:1 ratio. Fish had IV and IP catheters in place. Cmax=1.2 ug/ml at 9.1hr, AUC 31 ug/h/ml.
Citation:
J. Veterinary Pharmacology and Therapeutics 27:1-6
Link:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14995959
Genus Species:
Morone saxatilis x M. chrysops (hybrid)
Drug Class:
Antibiotic-Sulfa
t1/2-detail:
7.5 h
Wt gm-detail:
565-805 g
Water temp (°C)-detail:
16-17 C
Dosage-detail:
50 mg/kg sd
Method:
HPLC
Authors-red:
Bakal RS, Bai SA, Stoskopf MK
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