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U.S. Department of Health and Human Services

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Title:  Pharmacokinetics of sulphadimethoxine and ormetoprim in a 5:1 ratio following intraperitoneal and oral administration, in the hybrid striped bass (Morone chrysops x Morone saxitalis).
 
Authors:  Bakal RS, Bai SA, Stoskopf MK
 
Drug:  Sulfadimethoxine
 
Fish species:  Bass, striped (hybrid)
 
Date:  2004
 
t1/2-hr:  26
 
Sample:  blood, plasma
 
Ave Weight (gm):  685
 
Ave Water temp (°C):  17
 
Water:  Freshwater
 
Dosage:  50 mg/kg sd
 
Route:  IP
 
Comments:  Sulphadimethoxine and Ormetoprim in a 5:1 ratio. Fish had IV and IP catheters in place. Cmax=27.7 ug/ml at 3.6 hr, AUC 1141.8 ug/h/ml.
 
Citation:  J. Veterinary Pharmacology and Therapeutics 27:1-6
 
Link:  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14995959  Opens a new window
 
Genus Species:  Morone saxatilis x M. chrysops (hybrid)
 
Drug Class:  Antibiotic-Sulfa
 
t1/2-detail:  26 h
 
Wt gm-detail:  565-805 g
 
Water temp (°C)-detail:  16-17 C
 
Dosage-detail:  50 mg/kg sd
 
Method:  HPLC
 
Authors-red:  Bakal RS, Bai SA, Stoskopf MK
 
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