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U.S. Department of Health and Human Services

PhishPharm - Detail

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Title:  Distribution of emamectin benzoate in Atlantic salmon (Salmo salar L.).
 
Authors:  Sevatdal S, Magnusson A, Ingebrigtsen K, Haldorsen R, Horsberg TE.
 
Drug:  Emamectin
 
Fish species:  Salmon, Atlantic
 
Date:  2005
 
t1/2-hr:  720
 
est:  est
 
Sample:  blood
 
Ave Weight (gm):  202
 
Ave Water temp (°C):  7
 
Water:  Brackish
 
Dosage:  42.1 ug/kg sd
 
Route:  PO
 
Comments:  Salinity 2.2 ppt. (3H)Emamectin. Max concentration 14 ng/g at 7 d. (possibly plasma- elimination study used plasma but graphs show "blood"). T 1/2 estmated from graph, longer than when tested at 17 C.
 
Citation:  J. Veterinary Pharmacology and Therapeutics 28:101-107
 
Link:  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15720522&query_hl=4  Opens a new window
 
Genus Species:  Salmo salar
 
Drug Class:  Antiparasitic-Avermectin
 
t1/2-detail:  30 d est from graph
 
Wt gm-detail:  202 +/-31.0 g
 
Water temp (°C)-detail:  7+/-1°C
 
Dosage-detail:  42.1 ug/kg sd
 
Method:  HPLC-Rad
 
Authors-red:  Sevatdal S, Magnusson A, Ingebrigtsen K, Haldorsen R, Horsberg TE.
 
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