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U.S. Department of Health and Human Services

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Title:  Metabolism and depletion of albendazole in the muscle tissue of channel catfish following oral treatment.
Authors:  Shaikh B, Rummel N, Gieseker C, Reimschuessel R
Drug:  Albendazole
Fish species:  Catfish, channel
Date:  2006
t1/2-hr:  8
est:  est
Sample:  muscle
Ave Weight (gm):  896
Ave Water temp (°C):  25
Water:  Freshwater
Dosage:  10 mg/kg sd
Route:  PO
Comments:  Residues for ABZ 8h=11 ug/kg, 16h=ND, these results suggest that ABZ is absorbed poorly from the GI tract, and the absorbed drug is excreted rapidly in catfish. Unlike other species, no aminosulfone metabolite was detected. T1/2 field refers to parent (ABZ).
Metabolites:  ABZ-SO, ABZ-SO2, ABZ-2NH2SO2
Citation:  J. Veterinary Pharmacology and Therapeutics 29:525-530
Link:  http://onlinelibrary.wiley.com/doi/10.1046/j.0140-7783.2003.00534.x/abstract  Opens a new window
Genus Species:  Ictalurus punctatus
Drug Class:  Antiparasitic-Benzimidazole
t1/2-detail:  less than 8 h est
Wt gm-detail:  896+/-114 g
Water temp (°C)-detail:  25 +/-2 C
Dosage-detail:  10 mg/kg sd
Method:  HPLC
Authors-red:  Shaikh B, Rummel N, Gieseker C, Reimschuessel R