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Title:  Metabolism and depletion of albendazole in the muscle tissue of channel catfish following oral treatment.
 
Authors:  Shaikh B, Rummel N, Gieseker C, Reimschuessel R
 
Drug:  Albendazole
 
Fish species:  Catfish, channel
 
Date:  2006
 
t1/2-hr:  8
 
est:  est
 
Sample:  muscle
 
Ave Weight (gm):  896
 
Ave Water temp (°C):  25
 
Water:  Freshwater
 
Dosage:  10 mg/kg sd
 
Route:  PO
 
Comments:  Residues for ABZ-SO8h=5.2 ug/kg, 16h=ND, this suggests that oxidation of ABZ-SO to ABZ-SO2 is rapid. Unlike other species, no aminosulfone metabolite was detected. T1/2 field refers to ABZ-SO.
 
Metabolites:  ABZ-SO, ABZ-SO2, ABZ-2NH2SO2
 
Citation:  J. Veterinary Pharmacology and Therapeutics 29:525-530
 
Link:  http://onlinelibrary.wiley.com/doi/10.1046/j.0140-7783.2003.00534.x/abstract  Opens a new window
 
Genus Species:  Ictalurus punctatus
 
Drug Class:  Antiparasitic-Benzimidazole
 
t1/2-detail:  less than 8 h est
 
Wt gm-detail:  896+/-114 g
 
Water temp (°C)-detail:  25 +/-2 C
 
Dosage-detail:  10 mg/kg sd
 
Method:  HPLC
 
Authors-red:  Shaikh B, Rummel N, Gieseker C, Reimschuessel R
 
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