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U.S. Department of Health and Human Services

PhishPharm - Detail
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Title:  Studies on sulfonamides concentration in fishes I. Absorption of sulfonamides by gold fish from solution and their toxicity to the fish.
 
Authors:  Inoue S, Yoshida B, Imai S
 
Drug:  Sulfadimethoxine
 
Fish species:  Carp, crucian (goldfish)
 
Date:  1966
 
t1/2-hr:  48
 
est:  est
 
Sample:  whole body
 
Ave Weight (gm):  0
 
Ave Water temp (°C):  18
 
Water:  Freshwater
 
Dosage:  0.1%, 0.2% or 0.4% solution, 3, 6, 12, 24, 48 hrs
 
Route:  BATH
 
Comments:  0-1 year old fish, 70 mg/kg attained with 0.1% for 24 hrs, 0.2% or 0.4 % for 6 hrs, t1/2 est from graph.
 
Metabolites:  Sulfate, glucuronide
 
Citation:  Japanese Society of Scientific Fisheries 32:573-578
 
Link:  none  Opens a new window
 
Genus Species:  Carassius auratus auratus
 
Drug Class:  Antibiotic-Sulfa
 
t1/2-detail:  <48 hr
 
Wt gm-detail:  1 year old fish and 0 year old fish
 
Water temp (°C)-detail:  17.5-19.2 C
 
Dosage-detail:  0.1%, 0.2% or 0.4% solution, 3, 6, 12, 24, 48 hrs
 
Method:  Absorbance-Bratton&Marshall
 
Authors-red:  Inoue S, Yoshida B, Imai S
 
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