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U.S. Department of Health and Human Services

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Title:  A biologically based toxicokinetic model for pyrene in rainbow trout.
 
Authors:  Law FC, Abedini S, Kennedy CJ
 
Drug:  Pyrene
 
Fish species:  Trout, rainbow
 
Date:  1991
 
t1/2-hr:  72
 
est:  est
 
Sample:  gill
 
Ave Weight (gm):  450
 
Ave Water temp (°C):  10
 
Water:  Freshwater
 
Dosage:  10 mg/kg sd
 
Route:  IVC
 
Comments:  Cannulated fish. Approximate mean residues: 10h=7, 24h=3, 48h=2, 72h=2, 140h=0.5ug/g.
 
Citation:  Toxicology and Applied Pharmacology 110:390-402
 
Link:  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=1949009&query_hl=8  Opens a new window
 
Genus Species:  Oncorhynchus mykiss
 
Drug Class:  Organic-Hydrocarbon
 
t1/2-detail:  less than 72h estimated
 
Wt gm-detail:  450 g
 
Water temp (°C)-detail:  10+/-2°C
 
Dosage-detail:  10 mg/kg sd
 
Method:  HPLC-Rad
 
Authors-red:  Law FC, Abedini S, Kennedy CJ
 
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