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U.S. Department of Health and Human Services

PhishPharm - Detail

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Title:  A biologically based toxicokinetic model for pyrene in rainbow trout.
Authors:  Law FC, Abedini S, Kennedy CJ
Drug:  Pyrene
Fish species:  Trout, rainbow
Date:  1991
t1/2-hr:  72
est:  est
Sample:  intestinal tract-stomach-intestine-other*
Ave Weight (gm):  450
Ave Water temp (°C):  10
Water:  Freshwater
Dosage:  10 mg/kg sd
Route:  IVC
Comments:  *also included in this sample: esophagus, spleen-ventricle-red muscle. Cannulated fish. Approximate mean residues: 10h=4, 24h=3, 48h=2, 72h=1.5, 140h=0.05 ug/g.
Citation:  Toxicology and Applied Pharmacology 110:390-402
Link:  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=1949009&query_hl=8  Opens a new window
Genus Species:  Oncorhynchus mykiss
Drug Class:  Organic-Hydrocarbon
t1/2-detail:  less than 72h estimated
Wt gm-detail:  450 g
Water temp (°C)-detail:  10+/-2°C
Dosage-detail:  10 mg/kg sd
Method:  HPLC-Rad
Authors-red:  Law FC, Abedini S, Kennedy CJ