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U.S. Department of Health and Human Services

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Title:  Temperature dependence of Di-2-ethylhexyl phthalate (DEHP) pharmacokinetics in rainbow trout.
 
Authors:  Barron MG, Tarr BD, Hayton WL
 
Drug:  DEHP-(Di-2-Ethylhexyl Phthalate)
 
Fish species:  Trout, rainbow
 
Date:  1987
 
t1/2-hr:  90
 
est:  est
 
Sample:  blood, plasma
 
Ave Weight (gm):  356
 
Ave Water temp (°C):  12
 
Water:  Freshwater
 
Dosage:  400 µg/kg sd
 
Route:  IVC
 
Comments:  CL2= 40.6 ml/kg/hr, CL3= 3.4 ml/kg/hr, t 1/2 estimate from graph
 
Citation:  Toxicology and Applied Pharmacology 88:305-312
 
Link:  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=3576619&dopt=Abstract  Opens a new window
 
Genus Species:  Oncorhynchus mykiss
 
Drug Class:  Organic-Phtalate
 
t1/2-detail:  80 hr est
 
Wt gm-detail:  355.8 g
 
Water temp (°C)-detail:  12 C
 
Dosage-detail:  400 µg/kg sd
 
Method:  Rad
 
Authors-red:  Barron MG, Tarr BD, Hayton WL
 
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