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U.S. Department of Health and Human Services

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Title:  Sulfadimethoxine pharmacokinetics and metabolism in the channel catfish (Ictalurus punctatus).
 
Authors:  Squibb KS, Michel CMF, Zelikoff JT OConnor JM
 
Drug:  Sulfadimethoxine
 
Fish species:  Catfish, channel
 
Date:  1988
 
t1/2-hr:  29
 
Sample:  intestinal tract-bile
 
Ave Weight (gm):  0
 
Ave Water temp (°C):  0
 
Water:  Freshwater
 
Dosage:  40 mg/kg sd or SID 5 d
 
Route:  PO
 
Comments:  Multiple dosing was for 5d, After single dose = 107.3+/-1.0 h, multiple dosing = 29.2+/-0.3 h
 
Metabolites:  N-acetyl-metabolites in bile
 
Citation:  Veterinary and Human Toxicology 30 (supp 1):31-35
 
Link:  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=3212940&dopt=Abstract  Opens a new window
 
Genus Species:  Ictalurus punctatus
 
Drug Class:  Antibiotic-Sulfa
 
t1/2-detail:  After single dose = 107.3+/-1.0 h, multiple dosing = 29.2+/-0.3 h
 
Wt gm-detail:  Not specified
 
Water temp (°C)-detail:  Not Specified
 
Dosage-detail:  40 mg/kg sd or daily for 5 days
 
Method:  Rad
 
Authors-red:  Squibb KS, Michel CMF, Zelikoff JT OConnor JM
 
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