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U.S. Department of Health and Human Services

PhishPharm - Detail
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Title:  Disposition of sulfadimethoxine in the lobster.
 
Authors:  James MO, Barron MG
 
Drug:  Sulfadimethoxine
 
Fish species:  Lobster, American
 
Date:  1988
 
t1/2-hr:  77
 
Sample:  blood, hemolymph
 
Ave Weight (gm):  500
 
Ave Water temp (°C):  14
 
Water:  Saltwater
 
Dosage:  42 mg/kg sd
 
Route:  IPC
 
Comments:  Protein binding same at 14 and 203 ug sulfadimethoxine/ml hemolymph, Residues= 27.8 at 4 hr, 14.1 at 2 d, 1.34 ug/g tissue at 14 d.
 
Protein binding:  53.5
 
Cl:  0.014 L/kg/h
 
Vd:  1.43 L/kg
 
Citation:  Veterinary and Human Toxicology 30 (supp 1):36-40
 
Dep-time:  14 d
 
Link:  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=3212941&dopt=Abstract  Opens a new window
 
Genus Species:  Homarus americanus
 
Drug Class:  Antibiotic-Sulfa
 
t1/2-detail:  77 hr
 
Wt gm-detail:  400-600 g
 
Water temp (°C)-detail:  14+-2 C
 
Dosage-detail:  Intrapericardial 42/mg/kg sd
 
Method:  Absorbance-Bratton&Marshall
 
Authors-red:  James MO, Barron MG
 
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