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Title:
Disposition and metabolism of chloramphenicol in trout.
Authors:
Cravedi JP, Heuillet G, Peleran JC, Wal JM
Drug:
Chloramphenicol
Fish species:
Trout, rainbow
Date:
1985
t1/2-hr:
33
Sample:
urine
Ave Weight (gm):
225
Ave Water temp (°C):
17
Water:
Freshwater
Dosage:
50 mg/kg sd
Route:
PO
Comments:
t 1/2 -CP and CP glucuronide = 15-18h, CP base and CP alcohol = 30-33h. Whole carcass contained 7.5 % of initial dose after 5 days. Chloramphenicol (3H).
Protein binding:
Yes
Metabolites:
Chloramphenicol alcohol, CP glucuronide, CP base
Citation:
Xenobiotica 15:2:115-121
Link:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=4002733&dopt=Abstract
Genus Species:
Oncorhynchus mykiss
Drug Class:
Antibiotic-Phenicol
t1/2-detail:
CP and CP glucuronide = 15-18h, CP base and CP alcohol = 30-33h
Wt gm-detail:
200-250g
Water temp (°C)-detail:
17C
Dosage-detail:
50 mg/kg sd
Method:
Rad
Authors-red:
Cravedi JP, Heuillet G, Peleran JC, Wal JM
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