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U.S. Department of Health and Human Services

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Title:  Comparative pharmacokinetics and bioavailability of oxolinic acid oxytetracycline in rainbow trout (Oncorhynchus mykiss).
 
Authors:  Bjorklund HV, Bylund G (1991)
 
Drug:  Oxytetracycline
 
Fish species:  Trout, rainbow
 
Date:  1991
 
t1/2-hr:  60
 
Sample:  blood, plasma
 
Ave Weight (gm):  558
 
Ave Water temp (°C):  16
 
Water:  Freshwater
 
Dosage:  20 mg/kg sd
 
Route:  IV
 
Protein binding:  0.55
 
Cl:  0.016 L/kg/h
 
Vd:  1.34 L/kg
 
Citation:  Xenobiotica 21:1511-1520
 
Link:  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1763525&dopt=Abstract  Opens a new window
 
Genus Species:  Oncorhynchus mykiss
 
Drug Class:  Antibiotic-Tetracycline
 
t1/2-detail:  60.3h
 
Wt gm-detail:  558+/-24.6g
 
Water temp (°C)-detail:  16+/-0.5C
 
Dosage-detail:  20 mg/kg sd
 
Method:  HPLC
 
Authors-red:  Bjorklund HV, Bylund G (1991)
 
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