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Title:
Pharmacokinetics, bioavailability, plasma protein binding and disposition of nalidixic acid in Rainbow trout (Oncorhynchus mykiss).
Authors:
Jarobe H, Toth BR, Shoemaker KE, Greenless KJ, Kleinow KM.
Drug:
Nalidixic acid
Fish species:
Trout, rainbow
Date:
1993
t1/2-hr:
46
Sample:
blood, plasma
Ave Weight (gm):
1196
Ave Water temp (°C):
14
Water:
Freshwater
Dosage:
5 mg/kg sd
Route:
PO
Comments:
(14 C)Naladixic acid. Bioavailabilty 106.5 %
Citation:
Xenobiotica 23:961-972
Link:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=8291264&dopt=Abstract
Genus Species:
Oncorhynchus mykiss
Drug Class:
Antibiotic-Quinolone
t1/2-detail:
45.2 h
Wt gm-detail:
1196+/- 105 g g
Water temp (°C)-detail:
14+-1 C
Dosage-detail:
5 mg/kg sd
Method:
HPLC-Rad
Authors-red:
Jarobe H, Toth BR, Shoemaker KE, Greenless KJ, Kleinow KM.
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