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Title:
Absorption, tissue distribution, metabolism and excretion of ormetoprim and sulphadimethoxine in Atlantic salmon (Salmo salar) after intravenous and oral administration of Romet-30.
Authors:
Samuelsen OB, Ervik A, Wennevik V
Drug:
Ormetoprim
Fish species:
Salmon, Atlantic
Date:
1995
t1/2-hr:
26
Sample:
blood, plasma
Ave Weight (gm):
525
Ave Water temp (°C):
10
Water:
Saltwater
Dosage:
5/25 OMP/SDM mg/kg sd
Route:
IV
Comments:
(Romet-30)
Cl:
0.074 L/kg/h
Vd:
2.478 L/kg
Citation:
Xenobiotica 25:1169-1180
Link:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=8592867&dopt=Abstract
Genus Species:
Salmo salar
Drug Class:
Antibiotic-Sulfa
t1/2-detail:
25.6+/-1.26
Wt gm-detail:
450-600 g
Water temp (°C)-detail:
10 +/- 0.5 C
Dosage-detail:
5 mg/kg OMP and 25 mg/kg SDM (Romet-30) sd
Method:
HPLC
Authors-red:
Samuelsen OB, Ervik A, Wennevik V
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