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U.S. Department of Health and Human Services

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Title:  Effect of piperonyl butoxide on disposition of Di-2-ethylhexyl phthalate by rainbow trout.
 
Authors:  Melancon MJ Jr., Saybolt J, Lech JJ.
 
Drug:  DEHP-(Di-2-Ethylhexyl Phthalate)
 
Fish species:  Trout, rainbow
 
Date:  1977
 
Sample:  intestinal tract-bile
 
Ave Weight (gm):  100
 
Ave Water temp (°C):  0
 
Water:  Freshwater
 
Dosage:  1 mg/l Pip 24 hrs,followed by 0.07 mg/l DEHP and 1 mg/l Pip 24 hrs
 
Route:  BATH
 
Comments:  DEHP- (Di-2-ethylhexyl Phtalate)- fish pretreated with piperonyl butoxide had twice the concentrations of DEHP in muscle and half that in bile of fish treated only with DEHP. Residue in muscle control 0.021 vs bile 51.4 ug/g, in Pip treated muscle 0.041 vs bile 26.2 ug/g.
 
Citation:  Xenobiotica 7:633-640
 
Link:  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=910464&dopt=Abstract  Opens a new window
 
Genus Species:  Oncorhynchus mykiss
 
Drug Class:  Organic-Phtalate
 
Wt gm-detail:  Not Specified
 
Dosage-detail:  1 mg/l Pip for 24 hrs,followed by 0.07 mg/l DEHP and 1 mg/l Pip for 24 hrs
 
Method:  Rad
 
Authors-red:  Melancon MJ Jr., Saybolt J, Lech JJ.
 
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