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TITLE:  Residue depletion of albendazole and its metabolites in aquacultured yellow perch (Perca flavescens)
 
AUTHORS:  Yu D;Evans ER;Hasbrouck N;Reimschuessel R;Shaikh B;
 
YEAR:  2011
 
JOURNAL ABBREV:  J Vet Pharmacol Ther
 
MONTH:  Dec
 
TYPE:  JOUR
 
REFMAN INDEX:  642
 
JOURNAL FULL:  Journal of veterinary pharmacology and therapeutics
 
KEYWORDS:  Albendazole;Animals;Bass;CATFISH;CHANNEL CATFISH;drug;DRUGS;Food;FOOD ANIMALS;Hybrid striped bass;metabolism;MUSCLE;Perches;Research;RESIDUE;Residue depletion;Striped bass;TISSUE;veterinary;Veterinary Medicine;
 
ABSTRACT:  Yu, D., Evans, E. R., Hasbrouck, N., Reimschuessel, R., Shaikh, B. Residue depletion of albendazole and its metabolites in aquacultured yellow perch (Perca flavescens). J. vet. Pharmacol. Therap. doi: 10.1111/j.1365-2885.2011.01354.x. Metabolism and residue depletion studies are conducted to determine the marker residue (MR) of a drug in a target tissue of food animals. The MR is used to monitor potential unauthorized use of drugs. The current work is a continuation of our efforts to study metabolism and depletion profiles of albendazole in multiple finfish species to determine a common MR. The results of this study suggest that albendazole sulfone metabolite could potentially serve as MR for albendazole in yellow perch muscle, similar to channel catfish and hybrid striped bass as reported previously by us
 
AFFILIATIONS:  US Food and Drug Administration, Center for Veterinary Medicine, Office of Research, Laurel, MD, USA
 
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