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U.S. Department of Health and Human Services

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TITLE:  Comparison of molecular typing methods for the differentiation of Salmonella foodborne pathogens
 
AUTHORS:  Foley SL;Zhao S;Walker RD;
 
YEAR:  2007
 
JOURNAL ABBREV:  Foodborne Pathog Dis
 
TYPE:  JOUR
 
REFMAN INDEX:  493
 
JOURNAL FULL:  Foodborne pathogens and disease
 
VOLUME:  4
 
ISSUE:  3
 
START PAGE:  253
 
END PAGE:  276
 
KEYWORDS:  analysis;Bacteria;Bacterial Typing Techniques;classification;Dna;DNA,Bacterial;epidemiology;etiology;Food;Food Microbiology;Gene Amplification;Humans;methods;microbiology;Phylogeny;Polymerase Chain Reaction;Polymorphism,Restriction Fragment Length;Polymorphism,Single Nucleotide;Random Amplified Polymorphic DNA Technique;Research;Salmonella;Salmonella Food Poisoning;Species Specificity;
 
ABSTRACT:  Bacteria belonging to the genus Salmonella are among the leading causes of foodborne disease of bacterial etiology. These bacteria are also widely disseminated throughout the animal kingdom. The ability to identify the food source from which a human pathogen originated would be of great value in reducing the incidence of foodborne disease and the extent of disease outbreaks due to Salmonella. To date, efforts to identify the origin of these pathogens have centered on phenotypic and genotypic characterization of Salmonella isolates. This review focuses molecular or genotypic techniques that are currently being used for typing, and examines their strengths and weaknesses for determining the source of Salmonella foodborne infections
 
AFFILIATIONS:  National Farm Medicine Center, Marshfield Clinic Research Foundation, Marshfield, Wisconsin 54449, USA. foley.steven@mcrf.mfldclin.edu
 
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