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TITLE:  Variation within the vat(E) allele of Enterococcus faecium isolates from retail poultry samples
 
AUTHORS:  Simjee S;McDermott PF;Wagner DD;White DG;
 
YEAR:  2001
 
JOURNAL ABBREV:  Antimicrob Agents Chemother
 
MONTH:  Oct
 
TYPE:  JOUR
 
REFMAN INDEX:  256
 
JOURNAL FULL:  Antimicrobial agents and chemotherapy
 
VOLUME:  45
 
ISSUE:  10
 
START PAGE:  2931
 
END PAGE:  2932
 
KEYWORDS:  Acetyltransferases;Alleles;Amino Acid Sequence;Animals;Bacterial Proteins;Dna;Drug Resistance,Bacterial;Enterococcus;Enterococcus faecium;Food;Food Microbiology;Genetic Variation;genetics;isolation & purification;Meat;microbiology;Molecular Sequence Data;Poultry;Poultry Products;Proteins;Sequence Homology,Amino Acid;veterinary;Veterinary Medicine;
 
ABSTRACT:  In a survey of retail meat samples, twelve quinupristin-dalfopristin-resistant (MICs, > or =4 mg/liter) Enterococcus faecium isolates that carried a vat(E) gene were recovered. DNA sequence comparison revealed five new variations in the vat(E) allele among 12 isolates, which were designated vat(E-4) through vat(E-8); two isolates had vat(E-1). There was no correlation between the number of base changes and the quinupristin-dalfopristin MIC
 
AFFILIATIONS:  Division of Animal and Food Microbiology, Center for Veterinary Medicine, U.S. Food and Drug Administration, Laurel, MD 20708, USA. ssimjee@cvm.fda.gov
 
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