• Decrease font size
  • Return font size to normal
  • Increase font size
U.S. Department of Health and Human Services

CVM Publications - Detail

  • Print
  • Share
  • E-mail
-
 
TITLE:  Determination of pyrantel in swine liver by flame ionization gas chromatography and confirmation by gas chromatography/mass spectrometry
 
AUTHORS:  Tai SS;Cargile N;Barnes CJ;Kijak P;
 
YEAR:  1990
 
JOURNAL ABBREV:  J Assoc Off Anal Chem
 
MONTH:  Nov
 
TYPE:  JOUR
 
REFMAN INDEX:  483
 
JOURNAL FULL:  Journal - Association of Official Analytical Chemists
 
VOLUME:  73
 
ISSUE:  6
 
START PAGE:  883
 
END PAGE:  886
 
KEYWORDS:  analysis;Animals;chemistry;Chromatography;Drug Residues;Flame Ionization;Food;Food Contamination;Gas Chromatography-Mass Spectrometry;Laboratories;Liver;Meat;Molecular Structure;Pyrantel;Research;standards;Swine;
 
ABSTRACT:  During an evaluation of the gas chromatography/mass spectrometry (GC/MS) confirmatory procedure of Lynch and Bartolucci for pyrantel residues in swine tissues, we developed a GC flame ionization method for quantitating pyrantel residues in extracts of swine liver. The method was subjected to trial principally in the laboratories of Biospherics, Inc., using control liver, fortified control liver, and incurred liver tissue samples. Although the method does not meet all of the current Food and Drug Administration criteria, it compares favorably to the official determinative method. Portions of the same extract can be used for quantitation and for GC/MS confirmation, true recoveries appear to be slightly higher, and an internal standard is not required. The precision of this method equals or exceeds that of the official determinative method
 
AFFILIATIONS:  National Institute of Standards and Technology, Organic Analytical Research Division, Gaithersburg, MD 20899
 
-
-