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U.S. Department of Health and Human Services

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Article, Chapter, or Book Title:  Antimicrobial drug resistance
Author(s):  Martinez MN and Silley P
Year:  2010
Month:  April
Journal Abbrev, Book Title, or Conference:  Handb Exp Pharmacol
Journal Full Name:  Handbook of Experimental Pharmacology
Volume:  199
Start Page:  227
End Page:  264
Key Words:  microbial drug resistance, methods, alternative targets, drug concentrations, resistant, microbes
Abstract:  This review article summarizes the mechanisms of microbial drug resistance, how this resistance development can be encouraged by inadequate drug concentrations, and potential alternative targets that may help minimize the selection of resistant microbial strains.