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Article, Chapter, or Book Title:  Determination of an Oral Aflatoxin Dose that Acutely Impairs Hepatic Function in Domestic Pigeons (Columba livia)
Author(s):  Haley TL, Grizzle J, Rotstein DS, et al.
Year:  2010
Journal Abbrev, Book Title, or Conference:  J Avian Med Surg
Journal Full Name:  Journal of Avian Medicine and Surgery
Volume:  24
Start Page:  210
End Page:  221
Key Words:  aflatoxin B-1, hepatoxin, birds, model of hepatotoxicosis, Carneaux pigeons, mycotoxin, histopathological evaluation, liver, scintigraphy, bile acid testing
Abstract:  Aflatoxin B-1 is a common hepatotoxin in birds.¬†The study goal was to establish an acute model for hepatotoxicosis and decreased hepatic function in white Carneaux pigeons receiving an oral bolus of mycotoxoin, Aflatoxin B-1.¬†Evaluation included clinical pathology, scintigraphy, and histopathological evaluation of the liver.¬†Histological evaluation and liver enzyme activity indicated hepatocellular damage, but scintigraphy and bile acid testing did not demonstrate decreased hepatic function.