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U.S. Department of Health and Human Services

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Article, Chapter, or Book Title:  Glucagon-like peptide-2 (GLP-2) increases small intestinal blood flow and mucosal growth in ruminating calves
 
Author(s):  Taylor-Edwards CC, Burrin DG, Holst JJ, McLeod KR, Harmon DL
 
Year:  2011
 
Month:  Feb
 
Journal Abbrev, Book Title, or Conference:  J Dairy Sci
 
Journal Full Name:  Journal of Dairy Science
 
Issue:  2
 
Volume:  94
 
Start Page:  888
 
End Page:  898
 
Key Words:  glucagon-like peptide-2, calf, blood flow, small intestine
 
Abstract:  Glucagon-like peptide-2 (GLP-2) is a hormone secreted by intestinal endocrine cells in response to nutrients. Ruminant calves were given GLP-2 for 10 days, which increased small intestinal mucosal growth. Small intestinal blood flow increased with GLP-2, but the response was attenuated after the 10-day administration of GLP-2. This hormone may, in part, mediate physiological changes in the intestine that occur with diet and could benefit animals with intestinal disease.
 
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