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U.S. Department of Health and Human Services

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Article, Chapter, or Book Title:  Development of a Method to Detect Albendazole and Its Metabolites in the Muscle Tissue of Yellow Perch Using Liquid Chromatography with Fluorescence Detection
 
Author(s):  Yu D, Rummel N, and Shaikh B
 
Year:  2011
 
Month:  Mar-Apr
 
Journal Abbrev, Book Title, or Conference:  J AOAC Int
 
Journal Full Name:  Journal of the Association of Official Analytical Chemists (AOAC) International
 
Issue:  2
 
Volume:  94
 
Start Page:  446
 
End Page:  452
 
Key Words:  HPLC, albendazole, metabolites, sulfoxide, sulfone, albendazole-2-aminosulfone, yellow lake perch, muscle, skin
 
Abstract:  This article describes the development and validation of a new high performance liquid chromatographic (HPLC) method to analyze albendazole (ABZ) and its metabolites in muscle tissue of farm-raised Yellow Perch. The new method significantly shortens the analysis time compared to previous studies. All average recoveries for ABZ and its metabolites are within CVM guidelines.
 
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