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U.S. Department of Health and Human Services

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Article, Chapter, or Book Title:  Development of a Quantitative Multi-class/Multi-residue Method for 21 Veterinary Drugs in Shrimp
Author(s):  Hui L and Kijak PJ
Year:  2011
Month:  Mar-Apr
Journal Abbrev, Book Title, or Conference:  Journal of the AOAC International
Journal Full Name:  Journal of the AOAC International
Issue:  2
Volume:  94
Start Page:  394
End Page:  406
Key Words:  multiclass/multiresidue, shrimp, sulfonamides, tetracyclines, fluoroquinolones, cationic dyes, HPLC/MS/MS
Abstract:  A liquid chromatography-tandem mass spectrometry method was developed and validated to determine the concentration of 21 veterinary drug residues in shrimp meat. The chemicals belong to 5 different drug classes with significantly-varied chemical properties, and none of them has been approved in the U.S. for shrimp-farming. This method may be used either for new drug development (as a template for the regulatory residue method), or for surveillance purposes.