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U.S. Department of Health and Human Services

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Article, Chapter, or Book Title:  Anaphylactic events observed within 4 h of ocular application of an antibiotic-containing ophthalmic preparation: 61 cats (1993-2010)
 
Author(s):  Hume-Smith KM, Groth AD, Rishniw M, Walter-Grimm LA, Plunkett SJ, Maggs DJ
 
Year:  2011
 
Journal Abbrev, Book Title, or Conference:  J Feline Med Surg
 
Journal Full Name:  J Feline Med Surg
 
Issue:  10
 
Volume:  13
 
Start Page:  744
 
End Page:  751
 
Key Words:  anaphylaxis, ophthalmic antibiotics, Food and Drug Administration, cats
 
Abstract:  This study describes signalment, history, antibiotic administered, clinical signs observed, therapy, and outcome of anaphylactic events within 4 hours following ophthalmic administration of an antibiotic to cats. Data came from survey responses (45 cats) or U.S. Food and Drug Administration adverse drug event reports (16 cats). Although a causal association was not proved, ophthalmic antibiotic administration preceded anaphylaxis in all cats. Like other drugs, ophthalmic antibiotics should be used only when indicated.
 
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