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Article, Chapter, or Book Title:  Benzocaine-induced methemoglobinemia in an acute-exposure rat model
Author(s):  Von Tungeln LS, Zhou T, Woodling KA, Doerge DR, Greenlees KJ, and Beland FA
Year:  2011
Journal Abbrev, Book Title, or Conference:  Food and Chemical Toxicology
Journal Full Name:  Food and Chemical Toxicology
Issue:  10
Volume:  49
Start Page:  2,530
End Page:  2,539
Key Words:  rats, benzocaine, tricaine-methanesulfonate, methemoglobin
Abstract:  The study was conducted to determine if acute oral exposure to benzocaine could cause methemoglobinemia in rats. These data were used to estimate the potential impact of benzocaine residues in fish on the human consumer, and suggest that the consumption of fish treated with benzocaine hydrochloride will not cause methemoglobinemia in humans.