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Article, Chapter, or Book Title:  A systematic review of the safety of potassium bromide in dogs.
Author(s):  Hope E. Baird-Heinz, A'ndrea L. Van Schoick, Francis R. Pelsor, Lauren Ranivand, Laura L. Hungerford
Year:  2012
Month:  Mar
Journal Abbrev, Book Title, or Conference:  JAVMA
Journal Full Name:  Journal of the American Veterinary Medical Association
Issue:  6
Volume:  240
Start Page:  705
End Page:  715
Key Words:  Potassium bromide, KBr, epilepsy, seizures, therapy, dogs, phenobarbital, sodium bromide, review, toxicoses, adverse drug events
Abstract:  A systematic study of available literature was undertaken to critically evaluate and summarize available information on the safety of potassium bromide in dogs. Results suggested that potassium bromide is not an appropriate choice for treatment of every dog with seizures and that practitioners should tailor therapeutic regimens and clinical monitoring to each dog. Abrupt dietary changes or fluid therapy may compromise seizure control or increase the likelihood of adverse events. Availability of an appropriately labeled, approved potassium bromide product could provide better assurance for veterinarians and their clients of the quality, safety, and effectiveness of the product for veterinary use.