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U.S. Department of Health and Human Services

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Article, Chapter, or Book Title:  A systematic review of the safety of potassium bromide in dogs.
 
Author(s):  Hope E. Baird-Heinz, A'ndrea L. Van Schoick, Francis R. Pelsor, Lauren Ranivand, Laura L. Hungerford
 
Year:  2012
 
Month:  Mar
 
Journal Abbrev, Book Title, or Conference:  JAVMA
 
Journal Full Name:  Journal of the American Veterinary Medical Association
 
Issue:  6
 
Volume:  240
 
Start Page:  705
 
End Page:  715
 
Key Words:  Potassium bromide, KBr, epilepsy, seizures, therapy, dogs, phenobarbital, sodium bromide, review, toxicoses, adverse drug events
 
Abstract:  A systematic study of available literature was undertaken to critically evaluate and summarize available information on the safety of potassium bromide in dogs. Results suggested that potassium bromide is not an appropriate choice for treatment of every dog with seizures and that practitioners should tailor therapeutic regimens and clinical monitoring to each dog. Abrupt dietary changes or fluid therapy may compromise seizure control or increase the likelihood of adverse events. Availability of an appropriately labeled, approved potassium bromide product could provide better assurance for veterinarians and their clients of the quality, safety, and effectiveness of the product for veterinary use.
 
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