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U.S. Department of Health and Human Services

The Paper Trail
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Location: http://www.accessdata.fda.gov/scripts/sda/sdNavigation.cfm?sd=thepapertrail

The Paper Trail is a searchable database of journal articles, book chapters and posters authored or co-authored by employees of the FDA Center for Veterinary Medicine. Updated quarterly, the Paper Trail highlights the valuable research our scientists perform in their daily effort to protect human and animal health. For more information about an entry, such as the abstract, page numbers, and key words, click on its hyperlinked title in the far left column.

Download The Paper Trail data in Microsoft Excel web format Click on this link to download all data from the selected searchable database in Excel format. If you need help accessing information in different file formats, see Instructions for Downloading Viewers and Players.


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   No. of Records Found:  87
Article, Chapter, or Book Title Author(s) Year Journal Abbrev, Book Title, or Conference
Fahmy R. 2010 American Association for Pharmaceutical Scientists
Fahmy R. 2010 American Association for Pharmaceutical Scientists
Fahmy R. 2010 American Association for Pharmaceutical Scientists
Fahmy R. 2010 American Association for Pharmaceutical Scientists
Yu D, Evans ER, Hasbrouck N, Rummel N, Reimschuessel R, and Shaikh B. 2011 Middle Atlantic Regional Meeting (MARM) of the American Chemical Society
Swaim HL, Myers MJ, and Zhu M 2011 19th International Plant and Animal Genome Meeting
Fahmy R. 2010 American Association for Pharmaceutical Scientists
Fahmy R. 2010 American Association for Pharmaceutical Scientists
A Determinative and Confirmatory Method for Ceftiofur Metabolite Desfuroylceftiofur Cysteine Disulfide in Bovine Kidney by LC-MS/MS Feng S, Chattopadhaya C, Kijak P, Chiesa O, and Tall EA 2012 Journal of Chromatography B
Anaphylactic events observed within 4 h of ocular application of an antibiotic-containing ophthalmic preparation: 61 cats (1993-2010) Hume-Smith KM, Groth AD, Rishniw M, Walter-Grimm LA, Plunkett SJ, Maggs DJ 2011 J Feline Med Surg
Animal Drugs: Factors Influencing their Development and Use Martinez MN, Antonovic L, Dunham B, Fahmy R, Gilbert J, Hungerford L, Modric S, Papich M, Smith M, Yan SS 2012 APT
A No Observable Adverse Effects Level (NOAEL) for pigs fed melamine and cyanuric acid Stine CB, Reimschuessel R, Gieseker CM, Evans ER, Mayer TD, Hasbrouck NR, Tall E, Boehmer J, Gamboa da Costa G, Ward JL 2011 Regulatory Toxicology and Pharmacology
Antimicrobial drug resistance Martinez MN and Silley P 2010 Handb Exp Pharmacol
Antimicrobial Drug Resistance in Escherichia coli from Humans and Food Animals, United States, 19502002 Tadesse DA, Zhao S, Tong E, Ayers S, Singh A, Bartholomew MJ, McDermott PF. 2012 Emerging Infectious Diseases
Antimicrobial resistance and molecular subtyping of Campylobacter jejuni and Campylobacter coli from retail meats Wang X, Zhao S, Harbottle H, Tran T, Blickenstaff K, Abbott J, Meng J 2011 Journal of Food Protection
Antimicrobial resistance of Campylobacter isolates from retail meat in the United States between 2002 and 2007 Zhao S, Young SR, Tong E, Abbott JW, Womack N, Friedman SL, McDermott PF 2010 Appl Environ Microbiol
A single-laboratory validated method for the generation of DNA barcodes for the identification of fish for regulatory compliance. Handy SM, Deeds JR, Ivanova NV, Hebert PD, Hanner RH, Ormos A, Weigt LA, Moore MM, Yancy HF 2011 J AOAC Int
Assessing product bioequivalence for extended-release formulations and drugs with long half-lives Gehring R and Martinez MN 2012 J Vet Pharmacol Therap
Assessment of the critical factors affecting the porosity of roller compacted ribbons and the feasibility of using NIR chemical imaging to evaluate the porosity distribution Lim H, Dave VS, Kidder L, Lewis EN, Fahmy R, and Hoag SW 2011 International Journal of Pharmaceutics
A systematic review of the safety of potassium bromide in dogs. Hope E. Baird-Heinz, A'ndrea L. Van Schoick, Francis R. Pelsor, Lauren Ranivand, Laura L. Hungerford 2012 JAVMA
Benzocaine-induced methemoglobinemia in an acute-exposure rat model Von Tungeln LS, Zhou T, Woodling KA, Doerge DR, Greenlees KJ, and Beland FA 2011 Food and Chemical Toxicology
Bioaccumulation of Melamine in Catfish Muscle Following Continuous, Low-Dose, Oral Administration Andersen WC, Turnipseed SB, Karbiwnyk CM, Evans E, Hasbrouck N, Mayer TD, Gieseker CM, Nochetto C, Stine C, and Reimschuessel R. 2011 J Agric Food Chem
Bioavailability of Hydrophobic Organic Contaminants Hunter W, Gan J, Kookana R 2011 Soils and Sediments in Xing B, Senesi N, and Huang PM eds. Biophysico-Chemical Processes of Anthropogenic Organic Compounds in Environmental Systems Hoboken, NJ: John Wiley & Sons, Inc. 2011;517-534
Breakout session summary from AAPS/CRS joint workshop on critical variables in the in vitro and in vivo performance of parenteral sustained release products Martinez MN, Rathbone MJ, Burgess D, and Huynh M 2010 J Control Release
Comparative Genomics of 28 Salmonella enterica Isolates: Evidence for CRISPR-mediated Adaptive Sublineage Evolution Fricke WF, Mammel MK, McDermott PF, Tartera C, White DG, Leclerc JE, Ravel J, Cebula TA 2011 J Bacteriol
Comparative pharmacokinetics of enrofloxacin and ciprofloxacin in lactating dairy cows and beef steers following intravenous administration of enrofloxacin Idowu OR, Peggins JO, Cullison R, and von Bredow J 2010 Res Vet Sci
Considerations for extrapolating in vivo bioequivalence data across species and routes Modric S, Bermingham E, Heit M, Lainesse C, Thompson C 2012 J Vet Pharmacol Therap
Cryptococcus gattii vgi in a spinner dolphin (Stenella longirostris) from Hawaii Rotstein DS, West K, Levine G, et al 2010 J Zoo Wildl Me
Current challenges facing the determination of product bioequivalence in veterinary medicine Martinez MN and Hunter RP 2010 J Vet Pharm Ther
Demonstrating bioequivalence using clinical endpoint studies Bermingham E, DelCastillo JRE, Lainesse C, Paloske K, and Radecki S 2012 J Vet Pharmacol Therap
Determination of an Oral Aflatoxin Dose that Acutely Impairs Hepatic Function in Domestic Pigeons (Columba livia) Haley TL, Grizzle J, Rotstein DS, et al. 2010 J Avian Med Surg
Development and Validation of a Stability-indicating HPLC Method for the Estimation of L-tetrahydropalmatine in a Capsule Dosage Form Hepburn S, Lin Z , Wang JB , Fahmy R , and Hoag SW 2012
Development of a Method to Detect Albendazole and Its Metabolites in the Muscle Tissue of Yellow Perch Using Liquid Chromatography with Fluorescence Detection Yu D, Rummel N, and Shaikh B 2011 J AOAC Int
Development of a Quantitative Multi-class/Multi-residue Method for 21 Veterinary Drugs in Shrimp Hui L and Kijak PJ 2011 Journal of the AOAC International
Dose-response assessment of nephrotoxicity from a seven-day combined-exposure to melamine and cyanuric acid in F344 rats Jacob CC, Reimschuessel R, Von Tungeln LS, Olson GR, Warbritton AR, Hattan DG, Beland FA, and Gamboa da Costa G 2011 Toxicol Sci
Drug solubility classification in the bovine Martinez MN and Apley MD 2012 J Vet Pharmacol Therap
Drug solubility classification in the dog Martinez MN and Papich MG 2012 J Vet Pharmacol Therap
Effect of Coating Processing Parameters on the Dissolution Profiles of Ciprofloxacin HCl Controlled Release Multiparticulate Beads Kothari BH, Ashour A, Fahmy R, Moore C, and Hoag SW 2012
Effect of Humidity on the Coating Efficiency of Ciprofloxacin HCl Controlled Release Multiparticulate Beads Kothari BH, Jancsik B, Fahmy R, and Hoag SW 2012
Effects of Preprocessing Methods In Near Infrared Spectral Data for PLS Modeling of Chemical and Physical Properties of Intact Pharmaceutical Tablets Ashour A, Fahmy R, and Hoag SW 2012
Escherichia coli from retail meats carry genes associated with uropathogenic Escherichia coli, but are weakly invasive in human bladder cell culture Xia X, Meng J, McDermott PF, Zhao S 2011 Journal of Applied Microbiology
Estimating product bioequivalence for highly variable veterinary drugs Claxton R, Cook J, Endrenyi L, Lucas A, Martinez MN, and Sutton SC. 2012 J Vet Pharmacol Therap
Eudragit® RS PO/RL PO as rate-controlling matrix-formers via roller compaction: Influence of formulation and process variables on functional attributes of granules and tablets Dave VS, Fahmy R, Bensley D, and Hoag SW 2012 Drug Development and Industrial Pharmacy
Evolution and population structure of Salmonella enterica serovar Newport Sangal V, Harbottle H, Mazzoni CJ, Helmuth R, Guerra B, Didelot X, Paglietti B, Rabsch W, Brisse S, Weill FX, Roumagnac P, Achtman M 2010 J Bacteriol
Expression of mRNA for proglucagon and glucagon-like peptide-2 (GLP-2) receptor in the ruminant gastrointestinal tract and the influence of energy intake Taylor-Edwards CC, Burrin DG, Matthews JC, et al. 2010 Dom Anim Endocrinol
Glucagon-like peptide-2 (GLP-2) increases small intestinal blood flow and mucosal growth in ruminating calves Taylor-Edwards CC, Burrin DG, Holst JJ, McLeod KR, Harmon DL 2011 J Dairy Sci
Identification and antimicrobial resistance of extraintestinal pathogenic Escherichia coli from retail meats Xia X, Meng J, Zhao S, Bodeis-Jones S, Gaines SA, Ayers SL, McDermott PF 2011 J Food Prot
Interlaboratory evaluation of a real-time multiplex polymerase chain reaction method for identification of salmon and trout species in commercial products Rasmussen Hellberg RS, Naaum AM, Handy SM, Hanner RH, Deeds JR, Yancy HF, Morrissey MT 2011 Journal of Agriculture and Food Chemistry
Introduction to the bioequivalence theme issue Martinez MN and Hunter RP 2012 J Vet Pharmacol Therap
In vitro binding of enrofloxacin in human fecal slurries Ahn Y, Linder SW, Veach BT, Steve Yan S, Haydée Fernández A, Pineiro SA, Cerniglia CE 2012 Regul Toxicol Pharmacol
In vitro effect of seven antiparasitics on Acolpenteron ureteroecetes (Dactylogyridae) from largemouth bass Micropterus salmoides (Centrarchidae) Reimschuessel R, Gieseker C, Poynton S 2011 Diseases of Aquatic Organisms
In vivo characterization of inflammatory biomarkers in swine and the impact of flunixin meglumine administration Peters SM, Yancy HF, Deaver C, Jones YL, Kenyon E, Chiesa OA, Esparza J, Screven R, Lancaster V, Stubbs III, JT, Yancy M, Wiesenfeld PL, and Myers MJ 2012 Vet Immunol Immunopatho
Issues in Mass Spectrometry Between Bench Chemists and Regulatory Laboratory Managers: Summary of the Roundtable on Mass Spectrometry Heller DN 2010 Journal of AOAC International
Life Science Technologies: Lab Devices Get Smaller, More Intuitive, Less Expensive. Harding, A 2011 Science
Marker Residue Determination of Tritium-Labeled Ivermectin in the Muscle of Aquacultured Largemouth Bass, Hybrid Striped Bass and Yellow Perch following Oral Treatment Shaikh B, Rummel N, Yu D, Gieseker C, Evans E, Hasbrouck N, Reimschuessel R. 2012 J Agric Food Chem
Modeling lacaziosis lesion progression in common bottlenose dolphins Tursiops truncates using long-term photographic records Hart LB, Wells RS, Adams JD, Rotstein DS, et al 2010 Dis Aquat Organ
Molecular identification of animal species in food: Transition from research laboratories to the regulatory laboratories Myers MJ 2011 Vet J
Neurotoxic effects of ivermectin administration in genetically engineered mice with targeted insertion of the mutated canine ABCB1 gene Orzechowski KL, Swain MD, Robl MG, Tinaza CA, Swaim HL, Jones YL, Myers MJ, and Yancy HF 2012 Am J Vet Res
Novel insights about class 2 integrons from experimental and genomic epidemiology Ramírez MS, Piñeiro S, Centrón D, Argentinian Integron Study Group 2010 Antimicrob Agents Chemother
Novel methods for developing clinically relevant product specifications. Martinez MN, Selen A, and Jelliffe R 2010 Controlled Release Society Newsl
Oxytetracycline pharmacokinetics in rainbow trout during and after an orally administered medicated feed regimen Miller RA, Pelsor FR, Kane AS, and Reimschuessel R 2012 J Aquat Anim Health
Patient variation in veterinary medicine: Part I: Influence of altered physiological states Modric S and Martinez MN 2010 J Vet Pharm Ther
PDA Task Force for Alternative Mycoplasma Test Methods. Technical Report No. 50. Alternatives Methods for Mycoplasma Testing Davidson MK 2010 Parenteral Drug Association
Postmarket surveillance and regulatory considerations reproductive and developmental toxicology: an FDA perspective Bright SJ 2011 Gupta R, ed. Reproductive and Developmental Toxicology. Elsevier, Inc.
Prevalence and antimicrobial resistance profile of Campylobacter spp. isolated from conventional and antimicrobial-free swine production systems from different U.S. regions Tadesse DA, Bahnson PB, Funk JA, Thakur S, Morrow WE, Wittum T, DeGraves F, Rajala-Schultz P, Gebreyes WA 2011 Foodborne Pathogens and Disease
Prions and Prion Diseases Momcilovic D 2009 V.K. Juneja and J.N. Sofos (eds.) Pathogens and Toxins in Food: Challenges and Interventions, ASM Press, Washington D.C
Probability concepts in quality risk management Claycamp HG 2012 PDA J Pharm Sci Technol
Proteomic analysis of the temporal expression of bovine milk proteins during coliform mastitis and label-free relative quantification. Boehmer JL, Ward JL, Peters RR, et al. 2010 J Dairy Sci
Quality-by-Design I: Application of Failure Mode Effect Analysis (FMEA) and Plackett-Burman design of experiments in the identification of main factors in the formulation and process design space for roller compacted ciprofloxacin hydrochloride immediate release tablets. Fahmy R, Kona R, Dandu R, Xie W, Claycamp G, and Hoag SW 2012 AAPS PharmSciTech
Quality by Design and the Development of Solid Oral Dosage Forms Fahmy R, Danielson D, and Martinez M. 2012 Animal Health Drug Delivery
Real-Time PCR Assay for the Detection of Pufferfish Products Jones YL, Oliver HF, Deeds JR, and Yancy HF 2010 J Food Protection
Renal crystal formation after combined or sequential oral administration of melamine and cyanuric acid Reimschuessel R, Evans ER, Stine CB, Hasbrouck N, Mayer TD, Nochetto C, Gieseker CM 2010 Food Chem Toxicol
Safety of Antibiotic Drugs in Food Animals: Comparison of Findings from Preapproval Studies and Postapproval Experience in the United States with Safety Information in Published Literature Modric T, Modric S, Bright S, Murphy M, Shults S 2011 Veterinary Clinics of North America: Food Animal Practice; 27(2)
Should licking behavior be considered in the bioavailabilty evaluation of transdermal products? Toutain PL, Modric S, Bousquet-Mélou A, Sallovitz JM, Lanusse C 2012 J Vet Pharmacol Therap
Spectra ® fishing twine entanglement of a bottlenose dolphin: a case study and experimental modeling Barco SG, DEri LR, Woodward BL, Winn JP, and Rotstein DS 2010 Mar Pollution Bulletin
Study of physicomechanical properties of aqueous ethylcellulose dispersion films during the curing process Lin Z, Qu H, Kothari B, Chokshi R, Carlin B, Fahmy R, and Hoag SW 2012
Surveillance of Salmonella Prevalence in Animal Feeds and Characterization of the Salmonella Isolates by Serotyping and Antimicrobial Susceptibility Li X, Bethune LA, Jia A, Lovell RA, Proescholdt TA, Benz SA, Schell TC, Kaplan G, and McChesney DG 2012 Foodborne Pathogens and Disease
Surveillance of Salmonella Prevalence in Animal Feeds and Characterization of the Salmonella Isolates by Serotyping and Antimicrobial Susceptibility Li X, Bethune LA, Jia A, Lovell RA, Proescholdt TA, Benz SA, Schell TC, Kaplan G, and McChesney DG 2012
The Future: Modern Animal Biotechnology Rudenko L, Jones J, and Evdokimov E 2011 Davis RG, ed. Animal Diseases and Human Health: Saving Lives Now and in the Future
The Proteomic Advantage: Label-Free Quantification of Proteins Expressed in Bovine Milk during Experimentally Induced Coliform Mastitis. Boehmer JL, DeGrasse JA, McFarland MA, et al. 2010 Vet Immunol Immunopathol
The scientific basis for establishing solubility criteria for veterinary species Martinez MN and Fahmy R. 2012 J Vet Pharmacol Therap
Tissue/fluid correlation study for the depletion of sulfadimethoxine in bovine kidney, liver, plasma, urine, and oral fluid. Chiesa OA, Li H, Kijak P, et al. 2012 J Vet Pharmacol Therap
Toxicosis Caused by Melamine and Cyanuric Acid in Dogs and Cats: Uncovering the Mystery and Subsequent Global Implications Puschner B and Reimschuessel R 2011 Clinics in Laboratory Medicine
Toxicosis Caused by Melamine and Cyanuric Acid in Dogs and Cats: Uncovering the Mystery and Subsequent Global Implications Puschner B and Reimschuessel R 2011 Clinics in Laboratory Medicine 31(1):181-199
Treatment of Animal Toxicoses: A Regulatory Perspective Bright SJ, Murphy MM, Lovell RA, Steinschneider JC, Post LO 2011 Veterinary Clinics of North America: Food Animal Practice; 27(2)
vitro identification and verification of inflammatory biomarkers in swine Peters S, Yancy HF, Bremer E, Monroe J, Paul D, Stubbs III JT, and Myers MJ. 2011 Vet Immunol Immunopathol

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