MAUDE Adverse Event Report

This case was reported by a consumer and described the occurrence of worsening of liver cancer in a 78-year-old male patient who received poligrip (super poligrip original denture adhesive cream) over a period of two and one half months for loose dentures. A physician or other health care professional has not verified this report. The patient's past medical history included skin melanoma. Concurrent medical conditions included codeine allergy. Concurrent medications were unknown (unspecified medications). Approximately two and one half months prior to the report. In 2007, the patient started poligrip (dental). At an unknown time after starting poligrip, the patient experienced worsening of liver cancer. The patient reported that he was recently advised by his doctor that he had developed more nodules on his liver and the cancerous nodules were appearing faster then they were before. This case was assessed as medically serious by gsk. Treatment with poligrip was continued. At the time of reporting, the event was unresolved. Manufacturer's comment: the manufacturer report number for this case is 9681138-2007-00003. Super poligrip is manufactured in internationally. The lot number for this product is available, however, the product is not available. No corrective actions have been required based on this report.