CFR - Code of Federal Regulations Title 21

The information on this page is current as of Dec 22, 2023.

For the most up-to-date version of CFR Title 21, go to the Electronic Code of Federal Regulations (eCFR).

[Code of Federal Regulations]

[Title 21, Volume 6]

[CITE: 21CFR556.500]

TITLE 21--FOOD AND DRUGS

CHAPTER I--FOOD AND DRUG ADMINISTRATION
DEPARTMENT OF HEALTH AND HUMAN SERVICES

SUBCHAPTER E - ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS

PART 556 -- TOLERANCES FOR RESIDUES OF NEW ANIMAL DRUGS IN FOOD

Subpart B - Specific Tolerances for Residues of Approved and Conditionally Approved New Animal Drugs

Sec. 556.500 Oxytetracycline.

(a) Acceptable daily intake (ADI). The ADI for total tetracycline residues (chlortetracycline, oxytetracycline, and tetracycline) is 25 [micro]g/kg of body weight per day.

(b) Tolerances. The tolerances for the sum of tetracycline residues are:

(1) Cattle. (i) Muscle: 2 ppm.

(ii) Liver: 6 ppm.

(iii) Fat and kidney: 12 ppm.

(iv) Milk: 0.3 ppm.

(2) Chickens and turkeys. (i) Muscle: 2 ppm.

(ii) Liver: 6 ppm.

(iii) Fat and kidney: 12 ppm.

(3) Finfish. Muscle (with adhering skin when edible): 2 ppm.

(4) Lobster. Muscle: 2 ppm.

(5) Swine and sheep. (i) Muscle: 2 ppm.

(ii) Liver: 6 ppm.

(iii) Fat and kidney: 12 ppm.

(6) Honey. 750 ppb.

(c) Related conditions of use. See §§ 520.1660c, 520.1660d, 520.1664, 522.1660a, 522.1660b, 522.1662, 522.1664, 529.1660, 558.450, and 558.455 of this chapter.

[84 FR 32993, July 11, 2019, as amended at 85 FR 18121, Apr. 1, 2020; 88 FR 16549, Mar. 20, 2023, 88 FR 55567, Aug. 16, 2023]