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U.S. Department of Health and Human Services

Database of Select Committee on GRAS Substances (SCOGS) Reviews

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Sorbose (packaging)

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Report No.:  49
Type of Conclusion:  1
ID Code:  3615-56-3
Year:  1974
CFR Section:  186.1839
SCOGS Opinion:  The results of sorbose-feeding test with fasted rats showed no acute toxic effects for sorbose given excess of potential human dietary exposure. The metabolic products of sorbose metabolism in animals do not appear to include toxic substances and the chemical structure of sorbose does not suggest potential hazards. The results of the only study of the carcinogenicity of sorbose, involving parenteral administration in rats, have been judged by the investigator and reviewers to be negative. Based on these considerations, and the fact that sorbose is permitted only as an ingredient of cotton fabrics used in dry food packaging, the Select Committee concludes that: There is no evidence in the available information on sorbose that demonstrates, or suggests reasonable grounds to suspect, a hazard to the public when it is used at levels that are now current or that might reasonably be expected in future.