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U.S. Department of Health and Human Services

Database of Select Committee on GRAS Substances (SCOGS) Reviews

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Aconitic Acid

 
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Report No.:  41
 
Type of Conclusion:  1
 
ID Code:  499-12-7
 
Year:  1974
 
CFR Section:  184.1007
 
SCOGS Opinion:  The limited data on trans-aconitic acid indicate it to be less toxic than citric acid. Trans-aconitate salts appear to be excreted readily by the kidneys. There is no direct evidence that trans-aconitic acid is utilized as is the cis-aconitic acid isomer in mammalian metabolism although non-specific oxidation probably occurs. The Select Committee has weighed all of the foregoing and concludes that: There is no evidence in the available information on aconitic acid that demonstrates, or suggests reasonable grounds to suspect, a hazard to the public when it is used at levels that are now current or that might reasonably be expected in future.
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