GRAS Notice Inventory

The inventory of GRAS notices provides information about GRAS notices filed within each year since 1998, when FDA received its first GRAS notice. Once FDA has responded to a GRAS notice, the text of FDA's response will also be available as part of the record for that notice. We will update this information approximately monthly. More information about this inventory is available on the GRAS Notice Inventory Introduction page.

Records shown on this page: This page is a partial listing of all records in the database. Additional pages/records are available for selection at the bottom of the page. To view all records in the database select the All button at the bottom of the page. To search for a specific food ingredient, enter the term in the Search Criteria box and select Show Items to display only those records that contain the selected term. To view the text of the agency's response to the GRAS notice, select the text in the FDA's Letter column describing the response. Select the specific GRN number in the GRN No. column to view additional detail about any GRAS notice, including in some cases the submission itself. The agency has removed nondisclosable information from these submissions. All copyrighted information has also been removed and the bibliographic information listed in a reference table at the end of the submission.

GRN No. (select GRN No. for detailed record)	Substance	FDA's Letter (select to view letter)
304	Purified steviol glycosides with rebaudioside A and stevioside as the principal components	Pending
303	Rebaudioside A purified from the leaves of Stevia rebaudiana (Bertoni) Bertoni	Pending
302	1,3-propanediol	Pending
301	Siraitia grosvenorii (Luo han guo) fruit extract	Pending
300	Trisodium diphosphate	Pending
299	Lycopene from Escherichia coli expressing lycopene biosynthetic enzymes	At notifier's request, FDA ceased to evaluate the notice
298	Silicon dioxide	Pending
297	Erythritol fatty acid esters	Pending
296	Lipase enzyme preparation from a genetically modified Aspergillus niger expressing a modified lipase gene from Fusarium spp.	Pending
295	Aqueous extract of Emblica officinalis	Pending
294	Haematococcus pluvialis extract containing astaxanthin esters	Pending
293	Glutathione	Pending
292	Cellulase enzyme preparation derived from a genetically modified strain of Myceliophthora thermophila	FDA has no questions
291	Crystalline lutein	Pending
290	L-arginine	Pending
289	Colicin E1 purified from Escherichia coli	At notifier's request, FDA ceased to evaluate the notice
288	Lactobacillus rhamnosus strain HN001	Pending
287	Purified steviol glycosides with rebaudioside A and stevioside as the principal components	FDA has no questions
286	Galacto-oligosaccharides	FDA has no questions
285	Galacto-oligosaccharides	FDA has no questions
284	Bakers yeast mannoprotein	FDA has no questions
283	Stearidonic acid soybean oil	FDA has no questions
282	Rebaudioside A purified from the leaves of Stevia rebaudiana (Bertoni) Bertoni	FDA has no questions
281	Lactobacillus rhamnosus strain HN001 produced in a milk-based medium	FDA has no questions
280	Whole and milled flaxseed	FDA has no questions
279	Phosphatidylserine derived from fish	FDA has no questions
278	Rebaudioside A purified from the leaves of Stevia rebaudiana (Bertoni) Bertoni	FDA has no questions
277	Maltotetraohydrolase enzyme preparation from Bacillus licheniformis expressing a modified maltotetraohydrolase gene from Pseudomonas stutzeri	FDA has no questions
276	Dunaliella bardawil alga	At notifier's request, FDA ceased to evaluate the notice
275	Purified steviol glycosides with rebaudioside A as the principal component	FDA has no questions
274	Branching glycosyltransferase enzyme preparation from Bacillus subtilis expressing a branching glycosyltransferase gene from Rhodothermus obamensis	FDA has no questions
273	Baobab (Adansonia digitata) dried fruit pulp	FDA has no questions
272	Triple salt of magnesium, ammonium, and potassium chloride, hexahydrate	FDA has no questions
271	Ferrous ammonium phosphate	FDA has no questions
270	Polyglycerol polyricinoleic acid	FDA has no questions
269	Polyglycerol fatty acid esters with a degree of polymerization of 11 to 40 for the polyglycerol backbone	FDA has no questions
268	Bifidobacterium longum strain BB536	FDA has no questions
267	Protein glutaminase enzyme preparation derived from Chryseobacterium proteolyticum	FDA has no questions
266	Polyglycerol polyricinoleate	FDA has no questions
265	Glycerophospholipid cholesterol acyltransferase (GCAT) enzyme preparation from Bacillus licheniformis expressing a modified GCAT gene from Aeromonas salmonicida subsp. salmonicida	FDA has no questions
264	Sweet lupin flour	At notifier's request, FDA ceased to evaluate the notice
263	Sweet lupin fiber	At notifier's request, FDA ceased to evaluate the notice
262	Sweet lupin protein	At notifier's request, FDA ceased to evaluate the notice
261	Oat hull fiber	FDA has no questions
260	High-selenium yeast	FDA has no questions
259	Catechins from green tea extract	At notifier's request, FDA ceased to evaluate the notice
258	Sucromalt	FDA has no questions
257	gamma-Amino butyric acid	At notifier's request, FDA ceased to evaluate the notice
256	High linolenic acid flaxseed oil	FDA has no questions
255	Bovine globulin	FDA has no questions

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