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U.S. Department of Health and Human Services

GRAS Notice Inventory
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The inventory of GRAS notices provides information about GRAS notices filed within each year since 1998, when FDA received its first GRAS notice. Once FDA has responded to a GRAS notice, the text of FDA's response will also be available as part of the record for that notice. We will update this information approximately monthly. More information about this inventory is available on the GRAS Notice Inventory Introduction page.

Records shown on this page: This page is a partial listing of all records in the database. Additional pages/records are available for selection at the bottom of the page. To view all records in the database select the All button at the bottom of the page. To search for a specific food ingredient, enter the term in the Search Criteria box and select Show Items to display only those records that contain the selected term. To view the text of the agency's response to the GRAS notice, select the text in the FDA's Letter column describing the response. Select the specific GRN number in the GRN No. column to view additional detail about any GRAS notice, including in some cases the submission itself. The agency has removed nondisclosable information from these submissions. All copyrighted information has also been removed and the bibliographic information listed in a reference table at the end of the submission.





     No of Records Found:  465
GRN No.
(select GRN No. for detailed record)		 Substance FDA's Letter
(select to view letter)
415 Heat-killed Propionibacterium freudenreichii ET-3 culture (powder) FDA has no questions; some uses may require a color additive listing
414 L-lysine monohydrochloride FDA has no questions
413 Beta glucans derived from Ganoderma lucidum mycelium FDA has no questions
412 Chitin-glucan from Aspergillus niger FDA has no questions
411 Egg yolk-derived phospholipids FDA has no questions
410 Lactobacillus reuteri strain DSM 17938 FDA has no questions
409 Lactobacillus reuteri strain NCIMB 30242 At notifier's request, FDA ceased to evaluate the notice
408 Sulfuric acid and sodium sulfate FDA has no questions
407 Polysaccharide complex of konjac glucomannan (konjac), sodium alginate, and xanthan gum (polysaccharide complex KAX) FDA has no questions
406 1,4-α-glucan branching enzyme preparation from Bacillus subtilis strain 168 expressing the glucan branching enzyme gene from Aquifex aeolicus strain VF5 FDA has no questions
405 1,4-α-glucan branching enzyme preparation from Geobacillus stearothermophilus strain TRBE14 FDA has no questions
404 Cyclic dextrin, highly branched FDA has no questions
403 Carnallite sea salt (magnesium chloride, potassium chloride, salt) FDA has no questions
402 Peroxidase enzyme preparation derived from a genetically modified strain of Aspergillus niger FDA has no questions
401 Erythritol FDA has no questions
400 D-psicose FDA has no questions
399 Preparation of Bacillus coagulans strain GBI-30, 6086 spores FDA has no questions
398 Vegetable oil and tall oil derived phytosterol and phytosterol ester formulations FDA has no questions
397 Chitosan from Aspergillus niger FDA has no questions
396 Chlorella vulgaris strain Beij At notifier's request, FDA ceased to evaluate the notice
395 Steviol glycosides with rebaudioside A and stevioside as the principal components FDA has no questions
394 Dried biomass of Arthrospira platensis, also known as Spirulina platensis (Spirulina) FDA has no questions
393 Rebaudioside A purified from the leaves of Stevia rebaudiana (Bertoni) Bertoni (rebaudioside A) FDA has no questions
392 Oligofructose FDA has no questions
391 Spirulina (Anthrospira platensis) At notifier's request, FDA ceased to evaluate the notice
390 Suspended lutein FDA has no questions
389 Steviol glycosides with stevioside as the principal component FDA has no questions
388 Rebaudioside A purified from the leaves of Stevia rebaudiana (Bertoni) Bertoni (rebaudioside A) FDA has no questions
387 Plant-derived esterified and non-esterified sterols and stanols (phytosterols) FDA has no questions
386 Canola protein isolate and hydrolyzed canola protein isolate FDA has no questions
385 Lutein FDA has no questions
384 Algal oil derived from Chlorella protothecoides strain S106 (Cp algal oil) FDA has no questions
383 Magnesium dihydrogenpyrophosphate (MDPP) FDA has no questions
382 Erythritol FDA has no questions
381 Phytic acid FDA has no questions
380 Rebaudioside A purified from the leaves of Stevia rebaudiana (Bertoni) Bertoni (rebaudioside A) FDA has no questions
379 Tuna oil FDA has no questions
378 Cultured [dairy sources, sugars, wheat, malt, and fruit- and vegetable-based sources] fermented by [Streptococcus thermophilus, Bacillus coagulans, Lactobacillus acidophilus, Lactobacillus paracasei subsp. paracasei, Lactobacillus plantarum, Lactobacillus sakei, Lactobacillus bulgaricus and Proprionibacterium freudenreichii subsp. shermanii or mixtures of these strains] FDA has no questions
377 Bifidobacterium animalis subsp. lactis strain Bf-6 FDA has no questions
376 Milk mineral concentrate FDA has no questions
375 Enzyme-modified steviol glycosides FDA has no questions
374 Maleated isoprenyl polymer with methoxy-polyethylene glycol (MIP-MPEG) FDA has no questions
373 Rice bran fiber FDA has no questions
372 Glucoamylase enzyme preparation from Trichoderma reesei expressing the glucoamylase gene from T. reesei (glucoamylase enzyme preparation) FDA has no questions
371 Krill oil FDA has no questions
370 Xylooligosaccharide At notifier's request, FDA ceased to evaluate the notice
369 Rebaudioside A purified from the leaves of Stevia rebaudiana (Bertoni) Bertoni   FDA has no questions
368 Corn hull fiber At notifier's request, FDA ceased to evaluate the notice
367 Purified steviol glycosides with rebaudioside A and stevioside as the principal components FDA has no questions
366 Oat hull fiber At notifier's request, FDA ceased to evaluate the notice

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