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U.S. Department of Health and Human Services

GRAS Notice Inventory
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The inventory of GRAS notices provides information about GRAS notices filed within each year since 1998, when FDA received its first GRAS notice. Once FDA has responded to a GRAS notice, the text of FDA's response will also be available as part of the record for that notice. We will update this information approximately monthly. More information about this inventory is available on the GRAS Notice Inventory Introduction page.

Records shown on this page: This page is a partial listing of all records in the database. Additional pages/records are available for selection at the bottom of the page. To view all records in the database select the All button at the bottom of the page. To search for a specific food ingredient, enter the term in the Search Criteria box and select Show Items to display only those records that contain the selected term. To view the text of the agency's response to the GRAS notice, select the text in the FDA's Letter column describing the response. Select the specific GRN number in the GRN No. column to view additional detail about any GRAS notice, including in some cases the submission itself. The agency has removed nondisclosable information from these submissions. All copyrighted information has also been removed and the bibliographic information listed in a reference table at the end of the submission.





     No of Records Found:  465
GRN No.
(select GRN No. for detailed record)		 Substance FDA's Letter
(select to view letter)
365 Rebaudioside A purified from the leaves of Stevia rebaudiana (Bertoni) Bertoni (rebaudioside A)   FDA has no questions
364 Bacteriophages LAND12, OLB1, TSRW1, DSMP1, DP1 At notifier's request, FDA ceased to evaluate the notice
363 Calcium disodium ethylenediaminetetraacetic acid (EDTA) and disodium EDTA FDA has no questions
362 Levocarnitine At notifier's request, FDA ceased to evaluate the notice
361 1,4-α-D-glucan branching enzyme preparation At notifier's request, FDA ceased to evaluate the notice
360 Hydrolyzed sardine protein FDA has no questions
359 Siraitia grosvenorii Swingle (Luo Han Guo) fruit extracts (SGFE) FDA has no questions
358 Cyclic dextrin, highly branched At notifier's request, FDA ceased to evaluate the notice
357 Lactobacillus acidophilus NCFM FDA has no questions
356 Haematococcus pluvialis extract containing astaxanthin esters At notifier's request, FDA ceased to evaluate the notice
355 Eicosapentaenoic acid (EPA)-rich triglyceride oil from Yarrowia lipolytica FDA has no questions
354 Rebaudioside A purified from the leaves of Stevia rebaudiana (Bertoni) Bertoni (rebaudioside A) FDA has no questions
353 High-selenium yeast FDA has no questions
352 D-Tagatose FDA has no questions
351 Dunaliella bardawil FDA has no questions
350 Saccharomyces cerevisiae strain P1Y0, a variant of S. cerevisiae parent strain UCD2034 FDA has no questions
349 Purified steviol glycosides with rebaudioside A and stevioside as the principal components FDA has no questions
348 Stevioside purified from the leaves of Stevia rebaudiana (Bertoni) Bertoni (stevioside) FDA has no questions
347 Caffeine At notifier's request, FDA ceased to evaluate the notice
346 Freeze-dried fruit gac powder At notifier's request, FDA ceased to evaluate the notice
345 Carboxypeptidase enzyme preparation from modified Aspergillus niger FDA has no questions
344 Barley fiber FDA has no questions
343 Wheat bran extract composed primarily of xylo- and arabinoxylo-oligosaccharides FDA has no questions
342 Oat hull fiber FDA has no questions
341 Quercetin FDA has no questions; some uses may require a color additive listing
340 Theobromine At notifier's request, FDA ceased to evaluate the notice
339 Polyglutamic acid FDA has no questions
338 L-theanine extracted from tea leaves (Camellia sinensis) FDA has no questions
337 Enzyme-modified steviol glycosides preparation (EMSGP) FDA has no questions
336 ε-Polylysine (polylysine) FDA has no questions
335 Pine tree phytosterol esters FDA has no questions
334 Galacto-oligosaccharides FDA has no questions
333 Acid fungal protease enzyme preparation from Trichoderma reesei expressing the gene encoding acid fungal protease from T. reesei FDA has no questions
332 Oil from the seeds of the Korean pine (Pinus koraiensis) (Korean-pine nut oil) FDA has no questions
331 Algal oil (Chlorella protothecoides) At notifier's request, FDA ceased to evaluate the notice
330 Algal flour (Chlorella protothecoides) At notifier's request, FDA ceased to evaluate the notice
329 Rebaudioside A purified from the leaves of Stevia rebaudiana (Bertoni) Bertoni FDA has no questions
328 Polysaccharide complex of konjac glucomannan (konjac), sodium alginate, and xanthan gum (polysaccharide complex KAX) Notice does not provide a basis for a GRAS determination.
327 Cruciferin-rich canola/rapeseed protein isolate and napin-rich canola/rapeseed protein isolate FDA has no questions
326 Arachidonic acid rich oil from M. alpina strain I49-N18 FDA has no questions
325 Olestra FDA has no questions
324 Heat-killed Lactobacillus plantarum At notifier's request, FDA ceased to evaluate the notice
323 Purified steviol glycosides with rebaudioside A and stevioside as the principal components FDA has no questions
322 Aqueous extract of Emblica officinalis At notifier's request, FDA ceased to evaluate the notice
321 Synthetic amorphous silica FDA has no questions
320 Palm oil-derived carotenoids with β-carotene, α-carotene, γ-carotene, and lycopene FDA has no questions; some uses may require a color additive listing
319 Micro-algal oil Ulkenia sp. SAM2179 FDA has no questions; some uses may require a color additive listing
318 Rebaudioside A purified from the leaves of Stevia rebaudiana (Bertoni) Bertoni FDA has no questions
317 L-arginine FDA has no questions
316 Sodium potassium hexametaphosphate FDA has no questions

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