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U.S. Department of Health and Human Services

GRAS Notice Inventory
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The inventory of GRAS notices provides information about GRAS notices filed within each year since 1998, when FDA received its first GRAS notice. Once FDA has responded to a GRAS notice, the text of FDA's response will also be available as part of the record for that notice. We will update this information approximately monthly. More information about this inventory is available on the GRAS Notice Inventory Introduction page.

Records shown on this page: This page is a partial listing of all records in the database. Additional pages/records are available for selection at the bottom of the page. To view all records in the database select the All button at the bottom of the page. To search for a specific food ingredient, enter the term in the Search Criteria box and select Show Items to display only those records that contain the selected term. To view the text of the agency's response to the GRAS notice, select the text in the FDA's Letter column describing the response. Select the specific GRN number in the GRN No. column to view additional detail about any GRAS notice, including in some cases the submission itself. The agency has removed nondisclosable information from these submissions. All copyrighted information has also been removed and the bibliographic information listed in a reference table at the end of the submission.





     No of Records Found:  465
GRN No.
(select GRN No. for detailed record)		 Substance FDA's Letter
(select to view letter)
165 Quillaia extract type 1 FDA has no questions
164 Lauramide arginine ethyl ester FDA has no questions (additional correspondence available)
163 Tomato pulp powder FDA has no questions (additional correspondence available)
162 Lactoferrin (human) purified from rice At notifier's request, FDA ceased to evaluate the notice.
161 Chlorine dioxide, generated using sodium chlorite in calcined or sulfated kaolin clay FDA has no questions
160 Micro-algal oil (Ulkenia sp.) At notifier's request, FDA ceased to evaluate the notice.
159 Carnobacterium maltaromaticum strain CB1 FDA has no questions
158 Lipase preparation from Aspergillus niger expressing a gene encoding a lipase from Candida antartica FDA has no questions
157 Calcium propionate (alternative method of manufacture) FDA has no questions
156 Tomato lycopene extract 6 percent, tomato lycopene extract 1.5 percent, and crystallized tomato lycopene extract FDA has no questions (additional correspondence available); some uses may require a color additive listing
155 alpha-Cyclodextrin FDA has no questions
154 Dried orange pulp FDA has no questions
153 Conjugated linoleic acid At notifier's request, FDA ceased to evaluate the notice.
152 Sodium iron EDTA FDA has no questions
151 Ethanol (ethyl alcohol) FDA has no questions
150 Glucosamine hydrochloride prepared from chitin obtained from Aspergillus niger At notifier's request, FDA ceased to evaluate the notice.
149 Beta-glucanase enzyme preparation from Trichoderma harzianum FDA has no questions
148 Vegetable oil conjugated linoleic acid preparation At notifier's request, FDA ceased to evaluate the notice.
147 Extracted "seafood species" protein FDA has no questions (additional correspondence available)
146 Salmon oil FDA has no questions
145 Phospholipase A2 enzyme preparation from Streptomyces violaceoruber FDA has no questions
144 Adenosine 5'-monophosphoric acid and its monosodium and disodium salts FDA has no questions
143 Carbon monoxide FDA has no questions
142 Phospholipase enzyme preparation from Aspergillus oryzae expressing the gene encoding a phospholipase A1 from Fusarium venenatum FDA has no questions
141 Polyvinyl alcohol FDA has no questions
140 Crystalline lutein FDA has no questions; some uses may require a color additive listing
139 Cassia gum At notifier's request, FDA ceased to evaluate the notice.
138 Fish oil FDA has no questions
137 Algal oil (Schizochytrium sp.) FDA has no questions
136 Calcium gluconate FDA has no questions
135 ε-Polylysine FDA has no questions
134 Soy protein hydrolyzate with enzyme-modified lecithin FDA has no questions
133 Volatile oil of mustard FDA has no questions
132 Lactase enzyme preparation from Aspergillus niger FDA has no questions
131 High 2-palmitic vegetable oil FDA has no questions (additional correspondence available)
130 Bovine milk-derived lactoferrin FDA has no questions (additional correspondence available)
129 Sucrose fatty acid esters FDA has no questions
128 Skim milk or dextrose cultured with Propionibacterium freudenreichii subsp. shermanii FDA has no questions
127 Spirulina, the dried biomass of Arthrospira platensis FDA has no questions; some uses may require a color additive listing
126 Alpha-amylase enzyme preparation from Pseudomonas fluorescens Biovar I expressing a gene encoding a hybrid alpha-amylase derived from three microorganisms within the order Thermococcales FDA has no questions
125 Grape seed extract and grape pomace extract FDA has no questions; some uses may require a color additive listing
124 Grape seed extract FDA has no questions
123 Laminaria japonica broth and extract powder FDA has no questions
122 Laccase enzyme preparation produced by Aspergillus oryzae expressing the gene encoding a laccase from Myceliophthora thermophila FDA has no questions
121 Xanthan gum FDA has no questions
120 Saccharomyces cerevisiae strain ML01 carrying a gene encoding the malolactic enzyme from Oenococcus oeni and a gene encoding malate permease from Schizosaccharomyces pombe FDA has no questions
119 Synthetic lycopene FDA has no questions; some uses may require a color additive listing
118 Inulin FDA has no questions (additional correspondence available)
117 Ice structuring protein preparation FDA has no questions
116 Carrot fiber FDA has no questions

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