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U.S. Department of Health and Human Services

GRAS Notice Inventory
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The inventory of GRAS notices provides information about GRAS notices filed within each year since 1998, when FDA received its first GRAS notice. Once FDA has responded to a GRAS notice, the text of FDA's response will also be available as part of the record for that notice. We will update this information approximately monthly. More information about this inventory is available on the GRAS Notice Inventory Introduction page.

Records shown on this page: This page is a partial listing of all records in the database. Additional pages/records are available for selection at the bottom of the page. To view all records in the database select the All button at the bottom of the page. To search for a specific food ingredient, enter the term in the Search Criteria box and select Show Items to display only those records that contain the selected term. To view the text of the agency's response to the GRAS notice, select the text in the FDA's Letter column describing the response. Select the specific GRN number in the GRN No. column to view additional detail about any GRAS notice, including in some cases the submission itself. The agency has removed nondisclosable information from these submissions. All copyrighted information has also been removed and the bibliographic information listed in a reference table at the end of the submission.





     No of Records Found:  465
GRN No.
(select GRN No. for detailed record)		 Substance FDA's Letter
(select to view letter)
115 Diacylglycerol oil FDA has no questions
114 Pectate lyase enzyme preparation from Bacillus subtilis FDA has no questions
113 Lipase enzyme preparation from Aspergillus oryzae FDA has no questions
112 Phytosterols FDA has no questions
111 Lipase enzyme preparation from Aspergillus niger FDA has no questions
110 Lutein esters FDA has no questions; some uses may require a color additive listing
109 Tuna oil FDA has no questions
108 Glycerol ester of gum rosin Notice does not provide a basis for a GRAS determination
107 Polydextrose At notifier's request, FDA ceased to evaluate the notice
106 Glucose oxidase enzyme preparation from Aspergillus oryzae carrying a gene encoding a glucose oxidase from Aspergillus niger FDA has no questions
105 Fish oil concentrate FDA has no questions
104 Sucrose acetate isobutyrate FDA has no questions
103 Lipase enzyme preparation from Aspergillus oryzae carrying a gene constructed from a modified Thermomyces lanuginosus lipase gene and a portion of the Fusarium oxysporum lipase gene FDA has no questions
102 Small planktivorous pelagic fish body oil FDA has no questions
101 Spirulina At notifier's request, FDA ceased to evaluate the notice.
100 D-Ribose Notice does not provide a basis for a GRAS determination
99 Pullulan FDA has no questions
98 Small planktivorous pelagic fish body oil At notifier's request, FDA ceased to evaluate the notice.
97 Tuna oil At notifier's request, FDA ceased to evaluate the notice.
96 Silk protein food powder Notice does not provide a basis for a GRAS determination
95 Transglutaminase from Streptoverticillium mobaraense FDA has no questions
94 Docosahexaenoic acid-rich oil from tuna (DHA-rich tuna oil) and arachidonic acid-rich oil from Mortierella alpina (AA-rich fungal oil) FDA has no questions
93 Grape seed extract and grape skin extract Notice does not provide a basis for a GRAS determination.
92 Sucrose fatty acid esters Notice does not provide a basis for a GRAS determination.
91 Mycoprotein FDA has no questions
90 Carbohydrase enzyme preparation from Aspergillus oryzae, protease enzyme preparation from Aspergillus oryzae, and carbohydrase enzyme preparation from Rhizopus oryzae FDA has no questions (additional correspondence available)
89 Five enzyme preparations from Aspergillus niger: Carbohydrase enzyme preparation, catalase enzyme preparation, glucose oxidase enzyme preparation, pectinase enzyme preparation, and protease enzyme preparation FDA has no questions (additional correspondence available)
88 Invertase enzyme preparation from Saccharomyces cerevisiae and lactase enzyme preparation from Kluyveromyces marxianus FDA has no questions
87 Composite filtration media (diatomaceous earth and perlite) FDA has no questions
86 Coagulated potato protein, hydrolyzed potato protein, or clarified hydrolyzed potato protein FDA has no questions
85 Isoamylase from Pseudomonas amyloderamosa FDA has no questions
84 Arabinogalactan from Eastern Larch (Larix laricina) FDA has no questions
83 Carbon monoxide FDA has no questions
82 1,1,1,2-Tetrafluoroethane (HFC-134a) FDA has no questions
81 Lipase from Candida rugosa FDA has no questions
80 ARASCO (arachidonic acid-rich single-cell oil) FDA has no questions
79 Alpha-amylase derived from Bacillus licheniformis carrying a gene encoding a modified alpha-amylase from Bacillus licheniformis FDA has no questions
78 D-Tagatose FDA has no questions
77 Milk-derived lactoferrin FDA has no questions
76 Erythritol FDA has no questions
75 Lipase derived from Aspergillus oryzae carrying a gene encoding lipase from Fusarium oxysporum FDA has no questions
74 Beta-cyclodextrin FDA has no questions
73 Shrimp-derived chitosan At notifier's request, FDA ceased to evaluate the notice
72 Pullulanase derived from Bacillus licheniformis carrying a gene encoding pullulanase from B. deramificans FDA has no questions
71 White mineral oil, USP (viscosity ISO 100 ) FDA has no questions
70 Stearyl alcohol FDA has no questions
69 Behenic acid FDA has no questions
68 Lipase from Penicillium camembertii FDA has no questions
67 Milk-derived lactoferrin FDA has no questions
66 Milk thistle extract Notice does not provide a basis for a GRAS determination

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