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U.S. Department of Health and Human Services

GRAS Notice Inventory
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The inventory of GRAS notices provides information about GRAS notices filed within each year since 1998, when FDA received its first GRAS notice. Once FDA has responded to a GRAS notice, the text of FDA's response will also be available as part of the record for that notice. We will update this information approximately monthly. More information about this inventory is available on the GRAS Notice Inventory Introduction page.

Records shown on this page: This page is a partial listing of all records in the database. Additional pages/records are available for selection at the bottom of the page. To view all records in the database select the All button at the bottom of the page. To search for a specific food ingredient, enter the term in the Search Criteria box and select Show Items to display only those records that contain the selected term. To view the text of the agency's response to the GRAS notice, select the text in the FDA's Letter column describing the response. Select the specific GRN number in the GRN No. column to view additional detail about any GRAS notice, including in some cases the submission itself. The agency has removed nondisclosable information from these submissions. All copyrighted information has also been removed and the bibliographic information listed in a reference table at the end of the submission.





     No of Records Found:  465
GRN No.
(select GRN No. for detailed record)		 Substance FDA's Letter
(select to view letter)
465 Cow's milk-derived lactoferrin Pending
464 Cow's milk-derived lactoferrin Pending
463 Lactobacillus acidophilus strain NP 28, Lactobacillus acidophilus strain NP51, Lactobacillus subsp. lactis strain NP7, and Pediococcus acidilactici strain NP3 Pending
462 Lipase enzyme preparation from modified Pseudomonas fluorescens Biovar I Pending
461 Rebaudioside A purified from the leaves of Stevia rebaudiana (Bertoni) Bertoni (rebaudioside A) Pending
460 Curcuminoids purified from turmeric (Curcuma longa L.) Pending
459 Olive pulp extract Pending
458 Xylooligosaccharides Pending
457 Bacteriodes xylanisolvens strain DSM 23964 Pending
456 Rebaudioside D purified from the leaves of Stevia rebaudiana (Bertoni) Bertoni (rebaudioside D) Pending
455 Bifidobacterium breve M-16V Pending
454 Bifidobacterium breve M-16V Pending
453 Bifidobacterium breve M-16V Pending
452 Enzyme-modified steviol glycosides Pending
451 Calcium ascorbate/calcium threonate Pending
450 Chlorella protothecoides S106 flour with 40-70% lipid Pending
449 Medium chain triglycerides Pending
448 Enzyme-modified steviol glycosides Pending
447 Potato protein isolates Pending
446 Red grape pomace extract Pending
445 Bifidobacterium animalis subsp. lactis strains HN019, Bi-07, Bl-04 and B420 Pending
444 Milk protein concentrate and milk protein isolate Pending
443 Shrimp-derived chitosan At notifier's request, FDA ceased to evaluate the notice
442 Volatile oil of mustard (white) At notifier's request, FDA ceased to evaluate the notice
441 Sodium ferrous citrate Pending
440 Lactobacillus reuteri strain NCIMB 30242 FDA has no questions
439 Iron complex of tartaric acid At notifier's request, FDA ceased to evaluate the notice
438 Plant stanol esters FDA has no questions
437 Beta-glucans from oat bran FDA has no questions
436 Enzyme-modified dextrins FDA has no questions
435 Preparation consisting of six bacterial monophage specific to Salmonella enterica (monophage cocktail) FDA has no questions
434 Dried aqueous extract derived from white kidney bean (Phaseolus vulgaris) At notifier's request, FDA ceased to evaluate the notice
433 Poloxamer fatty acid esters At notifier's request, FDA ceased to evaluate the notice
432 Lutein diacetate FDA has no questions; some uses may require a color additive listing
431 Colostral whey protein concentrate At notifier's request, FDA ceased to evaluate the notice
430 Sugar beet fiber FDA has no questions
429 Lactobacillus casei strain Shirota FDA has no questions
428 Asparaginase enzyme preparation from genetically modified Aspergillus niger FDA has no questions
427 Corn hull fiber FDA has no questions
426 Rice hull fiber At notifier's request, FDA ceased to evaluate the notice
425 Canola oil (low erucic acid rapeseed oil) FDA has no questions
424 C-c-phycocyanin-enriched water extract of the cyanobacterium Arthrospira maxima or Arthrospira platensis, (also known as Spirulina maxima or Spirulina platensis) FDA has no questions; some uses may require a color additive listing
423 Cow's milk-derived lactoferrin At notifier's request, FDA ceased to evaluate the notice
422 Modified baker's yeast Saccharomyces cerevisiae FDA has no questions
421 Sucrose fatty acid esters FDA has no questions
420 Calcium acid pyrophosphate FDA has no questions
419 L-alpha-glycerylphosphorylcholine FDA has no questions
418 Rebaudioside A purified from the leaves of Stevia rebaudiana (Bertoni) Bertoni (rebaudioside A) FDA has no questions
417 Dried biomass of Arthrospira platensis also known as Spirulina platensis (spirulina) FDA has no questions
416 Lutein diacetate At notifier's request, FDA ceased to evaluate the notice
415 Heat-killed Propionibacterium freudenreichii ET-3 culture (powder) FDA has no questions; some uses may require a color additive listing
414 L-lysine monohydrochloride FDA has no questions
413 Beta glucans derived from Ganoderma lucidum mycelium FDA has no questions
412 Chitin-glucan from Aspergillus niger FDA has no questions
411 Egg yolk-derived phospholipids FDA has no questions
410 Lactobacillus reuteri strain DSM 17938 FDA has no questions
409 Lactobacillus reuteri strain NCIMB 30242 At notifier's request, FDA ceased to evaluate the notice
408 Sulfuric acid and sodium sulfate FDA has no questions
407 Polysaccharide complex of konjac glucomannan (konjac), sodium alginate, and xanthan gum (polysaccharide complex KAX) FDA has no questions
406 1,4-α-glucan branching enzyme preparation from Bacillus subtilis strain 168 expressing the glucan branching enzyme gene from Aquifex aeolicus strain VF5 FDA has no questions
405 1,4-α-glucan branching enzyme preparation from Geobacillus stearothermophilus strain TRBE14 FDA has no questions
404 Cyclic dextrin, highly branched FDA has no questions
403 Carnallite sea salt (magnesium chloride, potassium chloride, salt) FDA has no questions
402 Peroxidase enzyme preparation derived from a genetically modified strain of Aspergillus niger FDA has no questions
401 Erythritol FDA has no questions
400 D-psicose FDA has no questions
399 Preparation of Bacillus coagulans strain GBI-30, 6086 spores FDA has no questions
398 Vegetable oil and tall oil derived phytosterol and phytosterol ester formulations FDA has no questions
397 Chitosan from Aspergillus niger FDA has no questions
396 Chlorella vulgaris strain Beij At notifier's request, FDA ceased to evaluate the notice
395 Steviol glycosides with rebaudioside A and stevioside as the principal components FDA has no questions
394 Dried biomass of Arthrospira platensis, also known as Spirulina platensis (Spirulina) FDA has no questions
393 Rebaudioside A purified from the leaves of Stevia rebaudiana (Bertoni) Bertoni (rebaudioside A) FDA has no questions
392 Oligofructose FDA has no questions
391 Spirulina (Anthrospira platensis) At notifier's request, FDA ceased to evaluate the notice
390 Suspended lutein FDA has no questions
389 Steviol glycosides with stevioside as the principal component FDA has no questions
388 Rebaudioside A purified from the leaves of Stevia rebaudiana (Bertoni) Bertoni (rebaudioside A) FDA has no questions
387 Plant-derived esterified and non-esterified sterols and stanols (phytosterols) FDA has no questions
386 Canola protein isolate and hydrolyzed canola protein isolate FDA has no questions
385 Lutein FDA has no questions
384 Algal oil derived from Chlorella protothecoides strain S106 (Cp algal oil) FDA has no questions
383 Magnesium dihydrogenpyrophosphate (MDPP) FDA has no questions
382 Erythritol FDA has no questions
381 Phytic acid FDA has no questions
380 Rebaudioside A purified from the leaves of Stevia rebaudiana (Bertoni) Bertoni (rebaudioside A) FDA has no questions
379 Tuna oil FDA has no questions
378 Cultured [dairy sources, sugars, wheat, malt, and fruit- and vegetable-based sources] fermented by [Streptococcus thermophilus, Bacillus coagulans, Lactobacillus acidophilus, Lactobacillus paracasei subsp. paracasei, Lactobacillus plantarum, Lactobacillus sakei, Lactobacillus bulgaricus and Proprionibacterium freudenreichii subsp. shermanii or mixtures of these strains] FDA has no questions
377 Bifidobacterium animalis subsp. lactis strain Bf-6 FDA has no questions
376 Milk mineral concentrate FDA has no questions
375 Enzyme-modified steviol glycosides FDA has no questions
374 Maleated isoprenyl polymer with methoxy-polyethylene glycol (MIP-MPEG) FDA has no questions
373 Rice bran fiber FDA has no questions
372 Glucoamylase enzyme preparation from Trichoderma reesei expressing the glucoamylase gene from T. reesei (glucoamylase enzyme preparation) FDA has no questions
371 Krill oil FDA has no questions
370 Xylooligosaccharide At notifier's request, FDA ceased to evaluate the notice
369 Rebaudioside A purified from the leaves of Stevia rebaudiana (Bertoni) Bertoni   FDA has no questions
368 Corn hull fiber At notifier's request, FDA ceased to evaluate the notice
367 Purified steviol glycosides with rebaudioside A and stevioside as the principal components FDA has no questions
366 Oat hull fiber At notifier's request, FDA ceased to evaluate the notice
365 Rebaudioside A purified from the leaves of Stevia rebaudiana (Bertoni) Bertoni (rebaudioside A)   FDA has no questions
364 Bacteriophages LAND12, OLB1, TSRW1, DSMP1, DP1 At notifier's request, FDA ceased to evaluate the notice
363 Calcium disodium ethylenediaminetetraacetic acid (EDTA) and disodium EDTA FDA has no questions
362 Levocarnitine At notifier's request, FDA ceased to evaluate the notice
361 1,4-α-D-glucan branching enzyme preparation At notifier's request, FDA ceased to evaluate the notice
360 Hydrolyzed sardine protein FDA has no questions
359 Siraitia grosvenorii Swingle (Luo Han Guo) fruit extracts (SGFE) FDA has no questions
358 Cyclic dextrin, highly branched At notifier's request, FDA ceased to evaluate the notice
357 Lactobacillus acidophilus NCFM FDA has no questions
356 Haematococcus pluvialis extract containing astaxanthin esters At notifier's request, FDA ceased to evaluate the notice
355 Eicosapentaenoic acid (EPA)-rich triglyceride oil from Yarrowia lipolytica FDA has no questions
354 Rebaudioside A purified from the leaves of Stevia rebaudiana (Bertoni) Bertoni (rebaudioside A) FDA has no questions
353 High-selenium yeast FDA has no questions
352 D-Tagatose FDA has no questions
351 Dunaliella bardawil FDA has no questions
350 Saccharomyces cerevisiae strain P1Y0, a variant of S. cerevisiae parent strain UCD2034 FDA has no questions
349 Purified steviol glycosides with rebaudioside A and stevioside as the principal components FDA has no questions
348 Stevioside purified from the leaves of Stevia rebaudiana (Bertoni) Bertoni (stevioside) FDA has no questions
347 Caffeine At notifier's request, FDA ceased to evaluate the notice
346 Freeze-dried fruit gac powder At notifier's request, FDA ceased to evaluate the notice
345 Carboxypeptidase enzyme preparation from modified Aspergillus niger FDA has no questions
344 Barley fiber FDA has no questions
343 Wheat bran extract composed primarily of xylo- and arabinoxylo-oligosaccharides FDA has no questions
342 Oat hull fiber FDA has no questions
341 Quercetin FDA has no questions; some uses may require a color additive listing
340 Theobromine At notifier's request, FDA ceased to evaluate the notice
339 Polyglutamic acid FDA has no questions
338 L-theanine extracted from tea leaves (Camellia sinensis) FDA has no questions
337 Enzyme-modified steviol glycosides preparation (EMSGP) FDA has no questions
336 ε-Polylysine (polylysine) FDA has no questions
335 Pine tree phytosterol esters FDA has no questions
334 Galacto-oligosaccharides FDA has no questions
333 Acid fungal protease enzyme preparation from Trichoderma reesei expressing the gene encoding acid fungal protease from T. reesei FDA has no questions
332 Oil from the seeds of the Korean pine (Pinus koraiensis) (Korean-pine nut oil) FDA has no questions
331 Algal oil (Chlorella protothecoides) At notifier's request, FDA ceased to evaluate the notice
330 Algal flour (Chlorella protothecoides) At notifier's request, FDA ceased to evaluate the notice
329 Rebaudioside A purified from the leaves of Stevia rebaudiana (Bertoni) Bertoni FDA has no questions
328 Polysaccharide complex of konjac glucomannan (konjac), sodium alginate, and xanthan gum (polysaccharide complex KAX) Notice does not provide a basis for a GRAS determination.
327 Cruciferin-rich canola/rapeseed protein isolate and napin-rich canola/rapeseed protein isolate FDA has no questions
326 Arachidonic acid rich oil from M. alpina strain I49-N18 FDA has no questions
325 Olestra FDA has no questions
324 Heat-killed Lactobacillus plantarum At notifier's request, FDA ceased to evaluate the notice
323 Purified steviol glycosides with rebaudioside A and stevioside as the principal components FDA has no questions
322 Aqueous extract of Emblica officinalis At notifier's request, FDA ceased to evaluate the notice
321 Synthetic amorphous silica FDA has no questions
320 Palm oil-derived carotenoids with β-carotene, α-carotene, γ-carotene, and lycopene FDA has no questions; some uses may require a color additive listing
319 Micro-algal oil Ulkenia sp. SAM2179 FDA has no questions; some uses may require a color additive listing
318 Rebaudioside A purified from the leaves of Stevia rebaudiana (Bertoni) Bertoni FDA has no questions
317 L-arginine FDA has no questions
316 Sodium potassium hexametaphosphate FDA has no questions
315 Transglucosidase enzyme preparation from Trichoderma reesei expressing the gene encoding transglucosidase from Aspergillus niger FDA has no questions
314 Pork protein FDA has no questions
313 Beef protein FDA has no questions
312 Synthetic dihydrocapsiate FDA has no questions
311 Krill-based phosphatidylserine FDA has no questions; some uses may require a color additive listing
310 Potato fiber FDA has no questions
309 Beta-glucan derived from Aureobasidium pullulans FDA has no questions
308 L-leucine FDA has no questions
307 Palm oil-derived tocols with tocotrienols and α-tocopherol as the principal components FDA has no questions; some uses may require a color additive listing
306 Soybean oil with reduced palmitic and linolenic acids and increased oleic acid FDA has no questions
305 Carnobacterium maltaromaticum strain CB1 (viable and heat-treated) FDA has no questions
304 Purified steviol glycosides with rebaudioside A and stevioside as the principal components FDA has no questions
303 Rebaudioside A purified from the leaves of Stevia rebaudiana (Bertoni) Bertoni FDA has no questions
302 1,3-propanediol FDA has no questions
301 Siraitia grosvenorii Swingle (Luo Han Guo) fruit extract (SGFE) FDA has no questions
300 Trisodium diphosphate FDA has no questions
299 Lycopene from Escherichia coli expressing lycopene biosynthetic enzymes At notifier's request, FDA ceased to evaluate the notice
298 Silicon dioxide At notifier's request, FDA ceased to evaluate the notice
297 Erythritol fatty acid esters FDA has no questions
296 Lipase enzyme preparation from a genetically modified strain of Aspergillus niger FDA has no questions
295 Aqueous extract of Emblica officinalis At notifier's request, FDA ceased to evaluate the notice
294 Haematococcus pluvialis extract containing astaxanthin esters FDA has no questions; some uses may require a color additive listing
293 Glutathione FDA has no questions
292 Cellulase enzyme preparation derived from a genetically modified strain of Myceliophthora thermophila FDA has no questions
291 Crystalline lutein FDA has no questions
290 L-arginine FDA has no questions
289 Colicin E1 purified from Escherichia coli At notifier's request, FDA ceased to evaluate the notice
288 Lactobacillus rhamnosus strain HN001 FDA has no questions
287 Purified steviol glycosides with rebaudioside A and stevioside as the principal components FDA has no questions
286 Galacto-oligosaccharides FDA has no questions
285 Galacto-oligosaccharides FDA has no questions
284 Bakers yeast mannoprotein FDA has no questions
283 Stearidonic acid soybean oil FDA has no questions
282 Rebaudioside A purified from the leaves of Stevia rebaudiana (Bertoni) Bertoni FDA has no questions
281 Lactobacillus rhamnosus strain HN001 produced in a milk-based medium FDA has no questions
280 Whole and milled flaxseed FDA has no questions
279 Phosphatidylserine derived from fish FDA has no questions
278 Rebaudioside A purified from the leaves of Stevia rebaudiana (Bertoni) Bertoni FDA has no questions
277 Maltotetraohydrolase enzyme preparation from Bacillus licheniformis expressing a modified maltotetraohydrolase gene from Pseudomonas stutzeri FDA has no questions
276 Dunaliella bardawil alga At notifier's request, FDA ceased to evaluate the notice
275 Purified steviol glycosides with rebaudioside A as the principal component FDA has no questions
274 Branching glycosyltransferase enzyme preparation from Bacillus subtilis expressing a branching glycosyltransferase gene from Rhodothermus obamensis FDA has no questions
273 Baobab (Adansonia digitata) dried fruit pulp FDA has no questions
272 Triple salt of magnesium, ammonium, and potassium chloride, hexahydrate FDA has no questions
271 Ferrous ammonium phosphate FDA has no questions
270 Polyglycerol polyricinoleic acid FDA has no questions
269 Polyglycerol fatty acid esters with a degree of polymerization of 11 to 40 for the polyglycerol backbone FDA has no questions
268 Bifidobacterium longum strain BB536 FDA has no questions
267 Protein glutaminase enzyme preparation derived from Chryseobacterium proteolyticum FDA has no questions
266 Polyglycerol polyricinoleate FDA has no questions
265 Glycerophospholipid cholesterol acyltransferase (GCAT) enzyme preparation from Bacillus licheniformis expressing a modified GCAT gene from Aeromonas salmonicida subsp. salmonicida FDA has no questions (additional correspondence available)
264 Sweet lupin flour At notifier's request, FDA ceased to evaluate the notice
263 Sweet lupin fiber At notifier's request, FDA ceased to evaluate the notice
262 Sweet lupin protein At notifier's request, FDA ceased to evaluate the notice
261 Oat hull fiber FDA has no questions
260 High-selenium yeast FDA has no questions
259 Catechins from green tea extract At notifier's request, FDA ceased to evaluate the notice
258 Sucromalt FDA has no questions
257 gamma-Amino butyric acid At notifier's request, FDA ceased to evaluate the notice
256 High linolenic acid flaxseed oil FDA has no questions
255 Bovine globulin FDA has no questions
254 Lactobacillus reuteri strain DSM 17938 FDA has no questions
253 Rebaudioside A purified from Stevia rebaudiana (Bertoni) Bertoni FDA has no questions
252 Rebaudioside A purified from Stevia rebaudiana (Bertoni) Bertoni FDA has no questions
251 Carbon monoxide FDA has no questions
250 Plant sterols and stanols from pine trees FDA has no questions
249 Synthetic dihydrocapsiate FDA has no questions
248 Sucrose fatty acid esters (i.e., sucrose monoesters of lauric acid, palmitic acid, and stearic acid) manufactured by reaction of sucrose with vinyl esters of lauric, palmitic, and stearic acids FDA has no questions
247 Modified gum acacia FDA has no questions
246 Isomalto-oligosaccharide mixture FDA has no questions
245 Menaquinone-7 At notifier's request, FDA ceased to evaluate the notice
244 Glutathione At notifier's request, FDA ceased to evaluate the notice
243 D-Ribose FDA has no questions
242 Krill oil FDA has no questions; some uses may require a color additive listing
241 High-selenium yeast At notifier's request, FDA ceased to evaluate the notice
240 Corn, cane, or beet sugar cultured with Lactobacillus paracasei subsp. paracasei, Bacillus coagulans LA-1, or Propionibacterium freudenreichii subsp. shermanii, or mixtures of these microorganisms FDA has no questions
239 Bakers yeast beta-glucan FDA has no questions
238 Lipase enzyme preparation derived from Hansenula polymorpha expressing a gene encoding a lipase from Fusarium heterosporum FDA has no questions
237 Alkyl polyglycosides FDA has no questions
236 Galacto-oligosaccharides FDA has no questions
235 Human lactoferrin purified from rice At notifier's request, FDA ceased to evaluate the notice
234 Bovine globulin At notifier's request, FDA ceased to evaluate the notice
233 Combination of galacto-oligosaccharides and polydextrose FDA has no questions
232 Conjugated linoleic acid isomers FDA has no questions (additional correspondence available)
231 Lactobacillus casei subsp. rhamnosus strain GG FDA has no questions
230 Chymosin enzyme preparation from Trichoderma reesei expressing the bovine prochymosin B gene FDA has no questions
229 Methylsulfonylmethane FDA has no questions
228 Sodium nitrite embedded on one side of a food packaging film at a maximum level of 113 milligrams per square meter FDA has no questions
227 Olestra FDA has no questions
226 Lecithin derived from krill FDA has no questions
225 Catechins from green tea extract At notifier's request, FDA ceased to evaluate the notice
224 trans-Resveratrol At notifier's request, FDA ceased to evaluate the notice
223 Phosphatidylserine FDA has no questions
222 Citric acid esters of mono- and diglycerides FDA has no questions
221 Suspended lutein FDA has no questions; some uses may require a color additive listing
220 alpha-Glycosyl isoquercitrin FDA has no questions
219 Ammonium phosphatide FDA has no questions
218 Bacteriophage P100 preparation from Listeria innocua FDA has no questions
217 Tailored triglycerides containing approximately 12 percent medium-chain fatty acids FDA has no questions
216 Lipase enzyme preparation from Rhizopus oryzae FDA has no questions
215 Actinidia arguta extract FDA has no questions
214 Asparaginase enzyme preparation from Aspergillus niger expressing the asparaginase gene from A. niger FDA has no questions
213 Hydroxypropyl methylcellulose - expanded substitution pattern (HPMC-ESP) FDA has no questions
212 Phospholipase A2 enzyme preparation from Streptomyces violaceruber expressing a gene encoding phospholipase A2 from the same species FDA has no questions
211 Xanthan gum (lower pyruvate levels) FDA has no questions
210 Water soluble tomato concentrate FDA has no questions; some uses may require a color additive listing
209 L-theanine FDA has no questions
208 Erythritol FDA has no questions
207 Barley fiber FDA has no questions
206 Phytosterol esters and diglycerides resulting from transesterification of vegetable oils/fats with phytosterols FDA has no questions
205 Pullulanase enzyme preparation from Bacillus subtilis expressing the pullulanase gene from B. acidopullulyticus FDA has no questions
204 Phospholipase C enzyme preparation from Pichia pastoris expressing a heterologous phospholipase C gene FDA has no questions
203 Erythritol fatty acid esters At notifier's request, FDA ceased to evaluate the notice
202 Polyoxyethanyl-alpha-tocopheryl sebacate (PTS) FDA has no questions
201 Asparaginase enzyme preparation from Aspergillus oryzae expressing the asparaginase gene from A. oryzae FDA has no questions
200 Tailored triglycerides enriched in omega-3 fatty acids from fish oil FDA has no questions
199 Concentrated hydrolyzed milk protein FDA has no questions (additional correspondence available)
198 Bacteriophage P100 preparation from Listeria innocua FDA has no questions
197 Phosphatidylserine FDA has no questions
196 Bovine milk basic protein fraction FDA has no questions
195 Mixed beta-Glucanase and xylanase enzyme preparation from Humicola insolens FDA has no questions
194 Carbon monoxide FDA has no questions
193 Fish oil (predominantly sardine and anchovy); tuna oil FDA has no questions
192 High 2-palmitic vegetable oil FDA has no questions
191 Human lysozyme purified from rice At notifier's request, FDA ceased to evaluate the notice
190 Hydroxypropyl methylcellulose At notifier's request, FDA ceased to evaluate the notice
189 Lactoferrin (human) purified from bovine milk At notifier's request, FDA ceased to evaluate the notice
188 Carbon monoxide At notifier's request, FDA ceased to evaluate the notice
187 L(+) Tartaric acid (alternative method of manufacture) FDA has no questions
186 Soy lecithin enzymatically modified to have increased phosphatidylserine FDA has no questions
185 Concentrated tomato lycopene extract FDA has no questions; some uses may require a color additive listing
184 Isomaltulose FDA has no questions
183 Phospholipase A2 enzyme preparation from Aspergillus niger expressing a gene encoding a porcine phospholipase A2 FDA has no questions
182 Hydrolyzed wheat gluten isolate; pea protein isolate FDA has no questions
181 Phytosterols FDA has no questions
180 Allyl isothiocyanate FDA has no questions
179 Polyglycerol polyricinoleic acid FDA has no questions
178 Sodium iron EDTA FDA has no questions
177 Plant sterol esters FDA has no questions
176 Plant sterols and plant sterol esters from vegetable oils or sterols/stanols from tall oil FDA has no questions
175 Saccharomyces cerevisiae strain ECMo01 with enhanced expression of urea amidolyase FDA has no questions
174 Lysozyme (human) enzyme preparation from rice At notifier's request, FDA ceased to evaluate the notice.
173 Lycopene from Blakeslea trispora FDA has no questions; some uses may require a color additive listing
172 Isomalto-oligosaccharide At notifier's request, FDA ceased to evaluate the notice.
171 Lactobacillus acidophilus, Lactobacillus lactis, and Pediococcus acidilactici FDA has no questions (additional correspondence available)
170 Shrimp-derived chitosan At notifier's request, FDA ceased to evaluate the notice.
169 Bovine globulin At notifier's request, FDA ceased to evaluate the notice.
168 Poultry protein FDA has no questions
167 Carbon monoxide FDA has no questions
166 Carbon monoxide At notifier's request, FDA ceased to evaluate the notice.
165 Quillaia extract type 1 FDA has no questions
164 Lauramide arginine ethyl ester FDA has no questions (additional correspondence available)
163 Tomato pulp powder FDA has no questions (additional correspondence available)
162 Lactoferrin (human) purified from rice At notifier's request, FDA ceased to evaluate the notice.
161 Chlorine dioxide, generated using sodium chlorite in calcined or sulfated kaolin clay FDA has no questions
160 Micro-algal oil (Ulkenia sp.) At notifier's request, FDA ceased to evaluate the notice.
159 Carnobacterium maltaromaticum strain CB1 FDA has no questions
158 Lipase preparation from Aspergillus niger expressing a gene encoding a lipase from Candida antartica FDA has no questions
157 Calcium propionate (alternative method of manufacture) FDA has no questions
156 Tomato lycopene extract 6 percent, tomato lycopene extract 1.5 percent, and crystallized tomato lycopene extract FDA has no questions (additional correspondence available); some uses may require a color additive listing
155 alpha-Cyclodextrin FDA has no questions
154 Dried orange pulp FDA has no questions
153 Conjugated linoleic acid At notifier's request, FDA ceased to evaluate the notice.
152 Sodium iron EDTA FDA has no questions
151 Ethanol (ethyl alcohol) FDA has no questions
150 Glucosamine hydrochloride prepared from chitin obtained from Aspergillus niger At notifier's request, FDA ceased to evaluate the notice.
149 Beta-glucanase enzyme preparation from Trichoderma harzianum FDA has no questions
148 Vegetable oil conjugated linoleic acid preparation At notifier's request, FDA ceased to evaluate the notice.
147 Extracted "seafood species" protein FDA has no questions (additional correspondence available)
146 Salmon oil FDA has no questions
145 Phospholipase A2 enzyme preparation from Streptomyces violaceoruber FDA has no questions
144 Adenosine 5'-monophosphoric acid and its monosodium and disodium salts FDA has no questions
143 Carbon monoxide FDA has no questions
142 Phospholipase enzyme preparation from Aspergillus oryzae expressing the gene encoding a phospholipase A1 from Fusarium venenatum FDA has no questions
141 Polyvinyl alcohol FDA has no questions
140 Crystalline lutein FDA has no questions; some uses may require a color additive listing
139 Cassia gum At notifier's request, FDA ceased to evaluate the notice.
138 Fish oil FDA has no questions
137 Algal oil (Schizochytrium sp.) FDA has no questions
136 Calcium gluconate FDA has no questions
135 ε-Polylysine FDA has no questions
134 Soy protein hydrolyzate with enzyme-modified lecithin FDA has no questions
133 Volatile oil of mustard FDA has no questions
132 Lactase enzyme preparation from Aspergillus niger FDA has no questions
131 High 2-palmitic vegetable oil FDA has no questions (additional correspondence available)
130 Bovine milk-derived lactoferrin FDA has no questions (additional correspondence available)
129 Sucrose fatty acid esters FDA has no questions
128 Skim milk or dextrose cultured with Propionibacterium freudenreichii subsp. shermanii FDA has no questions
127 Spirulina, the dried biomass of Arthrospira platensis FDA has no questions; some uses may require a color additive listing
126 Alpha-amylase enzyme preparation from Pseudomonas fluorescens Biovar I expressing a gene encoding a hybrid alpha-amylase derived from three microorganisms within the order Thermococcales FDA has no questions
125 Grape seed extract and grape pomace extract FDA has no questions; some uses may require a color additive listing
124 Grape seed extract FDA has no questions
123 Laminaria japonica broth and extract powder FDA has no questions
122 Laccase enzyme preparation produced by Aspergillus oryzae expressing the gene encoding a laccase from Myceliophthora thermophila FDA has no questions
121 Xanthan gum FDA has no questions
120 Saccharomyces cerevisiae strain ML01 carrying a gene encoding the malolactic enzyme from Oenococcus oeni and a gene encoding malate permease from Schizosaccharomyces pombe FDA has no questions
119 Synthetic lycopene FDA has no questions; some uses may require a color additive listing
118 Inulin FDA has no questions (additional correspondence available)
117 Ice structuring protein preparation FDA has no questions
116 Carrot fiber FDA has no questions
115 Diacylglycerol oil FDA has no questions
114 Pectate lyase enzyme preparation from Bacillus subtilis FDA has no questions
113 Lipase enzyme preparation from Aspergillus oryzae FDA has no questions
112 Phytosterols FDA has no questions
111 Lipase enzyme preparation from Aspergillus niger FDA has no questions
110 Lutein esters FDA has no questions; some uses may require a color additive listing
109 Tuna oil FDA has no questions
108 Glycerol ester of gum rosin Notice does not provide a basis for a GRAS determination
107 Polydextrose At notifier's request, FDA ceased to evaluate the notice
106 Glucose oxidase enzyme preparation from Aspergillus oryzae carrying a gene encoding a glucose oxidase from Aspergillus niger FDA has no questions
105 Fish oil concentrate FDA has no questions
104 Sucrose acetate isobutyrate FDA has no questions
103 Lipase enzyme preparation from Aspergillus oryzae carrying a gene constructed from a modified Thermomyces lanuginosus lipase gene and a portion of the Fusarium oxysporum lipase gene FDA has no questions
102 Small planktivorous pelagic fish body oil FDA has no questions
101 Spirulina At notifier's request, FDA ceased to evaluate the notice.
100 D-Ribose Notice does not provide a basis for a GRAS determination
99 Pullulan FDA has no questions
98 Small planktivorous pelagic fish body oil At notifier's request, FDA ceased to evaluate the notice.
97 Tuna oil At notifier's request, FDA ceased to evaluate the notice.
96 Silk protein food powder Notice does not provide a basis for a GRAS determination
95 Transglutaminase from Streptoverticillium mobaraense FDA has no questions
94 Docosahexaenoic acid-rich oil from tuna (DHA-rich tuna oil) and arachidonic acid-rich oil from Mortierella alpina (AA-rich fungal oil) FDA has no questions
93 Grape seed extract and grape skin extract Notice does not provide a basis for a GRAS determination.
92 Sucrose fatty acid esters Notice does not provide a basis for a GRAS determination.
91 Mycoprotein FDA has no questions
90 Carbohydrase enzyme preparation from Aspergillus oryzae, protease enzyme preparation from Aspergillus oryzae, and carbohydrase enzyme preparation from Rhizopus oryzae FDA has no questions (additional correspondence available)
89 Five enzyme preparations from Aspergillus niger: Carbohydrase enzyme preparation, catalase enzyme preparation, glucose oxidase enzyme preparation, pectinase enzyme preparation, and protease enzyme preparation FDA has no questions (additional correspondence available)
88 Invertase enzyme preparation from Saccharomyces cerevisiae and lactase enzyme preparation from Kluyveromyces marxianus FDA has no questions
87 Composite filtration media (diatomaceous earth and perlite) FDA has no questions
86 Coagulated potato protein, hydrolyzed potato protein, or clarified hydrolyzed potato protein FDA has no questions
85 Isoamylase from Pseudomonas amyloderamosa FDA has no questions
84 Arabinogalactan from Eastern Larch (Larix laricina) FDA has no questions
83 Carbon monoxide FDA has no questions
82 1,1,1,2-Tetrafluoroethane (HFC-134a) FDA has no questions
81 Lipase from Candida rugosa FDA has no questions
80 ARASCO (arachidonic acid-rich single-cell oil) FDA has no questions
79 Alpha-amylase derived from Bacillus licheniformis carrying a gene encoding a modified alpha-amylase from Bacillus licheniformis FDA has no questions
78 D-Tagatose FDA has no questions
77 Milk-derived lactoferrin FDA has no questions
76 Erythritol FDA has no questions
75 Lipase derived from Aspergillus oryzae carrying a gene encoding lipase from Fusarium oxysporum FDA has no questions
74 Beta-cyclodextrin FDA has no questions
73 Shrimp-derived chitosan At notifier's request, FDA ceased to evaluate the notice
72 Pullulanase derived from Bacillus licheniformis carrying a gene encoding pullulanase from B. deramificans FDA has no questions
71 White mineral oil, USP (viscosity ISO 100 ) FDA has no questions
70 Stearyl alcohol FDA has no questions
69 Behenic acid FDA has no questions
68 Lipase from Penicillium camembertii FDA has no questions
67 Milk-derived lactoferrin FDA has no questions
66 Milk thistle extract Notice does not provide a basis for a GRAS determination
65 Nisin FDA has no questions
64 Egg white lysozyme FDA has no questions
63 Hops beta acids FDA has no questions
62 Chlorine dioxide generated from particles (<30μm) composed of sodium polyphosphate, magnesium sulfate, sodium silicate and sodium chlorite that are incorporated into low density polyethylene (LDPE) food-packaging films, at levels not exceeding 17.5 micrograms chlorite/in2 of finished package film FDA has no questions (additional correspondence available)
61 Plant sterols/Plant sterol esters FDA has no questions
60 Potassium bisulfate FDA has no questions
59 Hydrogenated starch hydrolysate At notifier's request, FDA ceased to evaluate the notice
58 Gum arabic At notifier's request, FDA ceased to evaluate the notice
57 Argon gas FDA has no questions
56 Diacylglycerol oil FDA has no questions
55 Transglutaminase from Streptoverticillium mobaraense FDA has no questions
54 Xylanase derived from Fusarium venenatum carrying a gene encoding xylanase from Thermomyces lanuginosus FDA has no questions
53 Phytosterol esters FDA has no questions
52 Whey mineral concentrate FDA has no questions
51 Cassia gum from Cassia tora/obtusifolia At notifier's request, FDA ceased to evaluate the notice.
50 Bohenin FDA has no questions
49 Bifidobacterium lactis strain Bb12 and Streptococcus thermophilus strain Th4 FDA has no questions (additional correspondence available)
48 Vegetable oil phytosterol esters FDA has no questions
47 Arabinogalactan from Larix occidentalis FDA has no questions
46 Gamma cyclodextrin FDA has no questions
45 Trehalose FDA has no questions
44 Fructooligosaccharide FDA has no questions (additional correspondence available)
43 Lipase derived from Aspergillus oryzae carrying a gene encoding lipase from Thermomyces lanuginosus FDA has no questions (additional correspondence available)
42 Milk-derived lactoferrin Notice does not provide a basis for a GRAS determination (additional correspondence available)
41 DHASCO (docosahexaenoic acid-rich single-cell oil) and ARASCO (arachidonic acid-rich single-cell oil) FDA has no questions
40 Mineral oil Notice does not provide a basis for a GRAS determination
39 Tall oil phytosterols FDA has no questions (additional correspondence available)
38 Cetylpyridinium chloride Notice does not provide a basis for a GRAS determination
37 Whey protein isolate and dairy product solids FDA has no questions (additional correspondence available)
36 Chromium picolinate; Ginkgo biloba leaf extract; and Ginseng extract At notifier's request, FDA ceased to evaluate the notice
35 Hempseed oil Notice does not provide a basis for a GRAS determination
34 Aspartic proteinase derived from Aspergillus oryzae carrying a gene encoding aspartic proteinase from Rhizomucor miehei FDA has no questions
33 Low erucic acid oil derived from Brassica juncea FDA has no questions
32 Pectin lyase derived from Trichoderma reesei carrying a gene encoding pectin lyase from Aspergillus niger FDA has no questions
31 Cetylpyridinium chloride At notifier's request, FDA ceased to evaluate the notice.
30 Crospovidone-cranberry juice extract Notice does not provide a basis for a GRAS determination (additional correspondence available)
29 Transglutaminase from Streptoverticillium mobaraense FDA has no questions
28 Seaweed-derived calcium FDA has no questions (additional correspondence available)
27 Dextranase from Chaetomium gracile FDA has no questions
26 Isolated wheat protein FDA has no questions
25 Extract of Garcinia kola seed ("bitter cola") Notice does not provide a basis for a GRAS determination
24 alpha-Amylase derived from Bacillus licheniformis carrying a gene encoding alpha-amylase from Bacillus stearothermophilus FDA has no questions
23 Protein preparation from animal blood At notifier's request, FDA ceased to evaluate the notice
22 alpha-Amylase derived from Bacillus licheniformis carrying a gene encoding a modified alpha-amylase derived from Bacillus lichenformis and Bacillus amyloliquefaciens FDA has no questions
21 Pork collagen FDA has no questions
20 Pullulanase derived from Bacillus subtilis carrying a gene encoding pullulanase from Bacillus naganoensis FDA has no questions
19 Ferrous bisglycinate chelate FDA has no questions
18 Mesquite (Prosopis spp.) wood alcoholic extract FDA has no questions
17 Arabinogalactan At notifier's request, FDA ceased to evaluate the notice.
16 Menhaden oil At notifier's request, FDA ceased to evaluate the notice
15 Tasteless smoke FDA has no questions
14 Hydrogen peroxide Notice does not provide a basis for a GRAS determination
13 Botanicals: Chrysanthemum; Licorice; Jellywort AND
Honeysuckle; Lophatherum; Mulberry leaf; Frangipani; Selfheal; Sophora flower bud		 FDA has no questions AND
Notice does not provide a basis
12 Mesquite wood alcoholic extract At notifier's request, FDA ceased to evaluate the notice.
11 Calcium casein peptone-calcium phosphate FDA has no questions
10 Exopeptidase derived from Aspergillus oryzae carrying a gene encoding a leucine aminopeptidase from Aspergillus sojae Notice does not provide a basis for a GRAS determination
9 Polyglycerol polyricinoleic acid FDA has no questions
8 Pectin esterase derived from Aspergillus oryzae carrying a gene encoding pectin esterase from Aspergillus aculeatus FDA has no questions
7 ARASCO (arachidonic acid-rich single-cell oil) and DHASCO (docosahexaenoic acid-rich single-cell oil) as sources of the fatty acids ARA (arachidonic acid) and DHA (docosahexaenoic acid) Notice does not provide a basis for a GRAS determination.
6 Dioctyl sodium sulfosuccinate FDA has no questions
5 Tasteless smoke At notifier's request, FDA ceased to evaluate the notice.
4 Transglutaminase from Streptoverticillium mobaraense FDA has no questions
3 Sodium bisulfate FDA has no questions
2 Solin oil (low linolenic acid flaxseed oil or low linolenic acid linseed oil) FDA has no questions
1 Soy isoflavone extract At notifier's request, FDA ceased to evaluate the notice

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