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U.S. Department of Health and Human Services

List of Indirect Additives Used in Food Contact Substances
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Please note that by being listed below, no inference should be made about the legality of using any one of these specific substances as an "indirect" food additive. Their presence on this list only indicates that the names of these substances are found (or, in the case of some of the polymers, are implied) in 21CFR parts 175 - 178. The regulation(s) cited for a substance should always be consulted for the complete context before any conclusion is made as to allowed regulated use. To access the specific regulations listed below, type in the title number, 21, and then the section and part numbers, e.g. 175 and 105 at the Government Printing Office web site.

Definitions of the labels that are found in this inventory are:

LabelDefinition
DOCNUMThe PAFA database number
MAINTERMThe name of the substance as recognized by CFSAN
CAS RN OR OTHER CODEChemical Abstract Service (CAS) Registry Number for the substance or a numerical code assigned by CFSAN to those substances that do not have a CAS Registry Number (888nnnnnn or 977nnnnnn-series)
REGNUMRegulation numbers in Title 21 of the U.S. Code of Federal Regulations where the substance appears. (Note that if a substance is mentioned in 21CFR parts 175 - 178 and, thus, is listed below, any other citations for the same substance in other sections of 21CFR dealing with food additives (parts 1 - 199 inclusive) are also cited.)




     No of Records Found:  3,237
Doc No. Mainterm CAS RN or Other Code Regnum
8431 N-(2-AMINOETHYL)-1,3-PROPANEDIAMINE 13531-52-7 176.180
5967 N-(6-AMINOHEXYL)-1,6-HEXANEDIAMINE 143-23-7 175.105
5054 2-AMINO-2-METHYL-1-PROPANOL 124-68-5 175.105
176.170
5055 AMINOMETHYLSULFONIC ACID 13881-91-9 176.180
5799 3-AMINOMETHYL-3,5,5-TRIMETHYLCYCLOHEXYLAMINE 2855-13-2 175.105
175.300
5056 3-AMINO-1,2-PROPANEDIOL 616-30-8 175.105
7899 1-AMINO-2-PROPANOL HYDROCHLORIDE 7780-04-3 176.180
5058 11-AMINOUNDECANOIC ACID 2432-99-7 177.1200
177.1500
5059 AMMONIA 7664-41-7 176.170
176.210
6309 AMMONIA/ETHYLENE DICHLORIDE/SODIUM HYDROXIDE POLYETHYLENEAMINE MIXTURE 977138-17-2 176.170
5060 AMMONIUM ACRYLATE 10604-69-0
5061 AMMONIUM BENZOATE 1863-63-4 175.105
5062 AMMONIUM BIFLUORIDE 1341-49-7 175.105
7088 AMMONIUM 5,5-BIS((PERFLUOROALKYL(C2-18)ETHYL)THIOMETHYL)-2-HYDROXY-2-OXO-1,3,2-DIOXAPHOSPHORINANE 977169-38-2 176.170
5063 AMMONIUM BIS(N-ETHYL-2-PERFLUOROALKYLSULFONAMIDOETHYL) PHOSPHATE 977094-93-1
5064 AMMONIUM BIS(2-(N-ETHYL(PERFLUOROOCTANE)SULFONAMIDO)ETHYL) PHOSPHATE 30381-98-7 176.170
7102 AMMONIUM BIS(2,2-BIS((PERFLUOROALKYL(C2-18)ETHYL)THIOMETHYL)-3 HYDROXYPROPYL) PHOSPHATE 977169-39-3 176.170
5065 AMMONIUM BORATE 12007-58-8 175.105
5066 AMMONIUM 9,10-EPOXYSTEARATE 61792-39-0 178.3400
7721 AMMONIUM FRUCTOHEPTONATE 977182-69-6 176.150
5068 AMMONIUM GLUCOHEPTONATE 100897-12-9 176.150
5069 AMMONIUM HEXAFLUOROSILICATE 16919-19-0 175.105
5070 AMMONIUM ION 14798-03-9
5072 AMMONIUM LAURYL SULFATE 2235-54-3 175.105
175.210
176.170
177.1200
5073 AMMONIUM MONO(N-ETHYL-2-PERFLUOROALKYLSULFONAMIDOETHYL) PHOSPHATE 977094-94-2 176.170
5074 AMMONIUM NITRATE 6484-52-2 176.180
5077 AMMONIUM OCTOXYNOL 40 MONOHYDROGEN PHOSPHATE 977097-37-2 175.105
176.180
5078 AMMONIUM OCTOXYNOL 6-9 MONOHYDROGEN PHOSPHATE 977097-36-1 175.105
176.180
5079 AMMONIUM POLYACRYLATE 9003-03-6 175.105
5080 AMMONIUM POTASSIUM HYDROGEN PHOSPHATE 10279-61-5 175.105
175.300
181.29
5081 AMMONIUM SULFAMATE 7773-06-0 175.105
5082 AMMONIUM THIOCYANATE 1762-95-4 175.105
5083 AMMONIUM THIOSULFATE 7783-18-8 175.105
176.170
7082 AMMONIUM ZIRCONIUM CITRATE HYDROXY LACTATE 149564-64-7 176.170
7081 AMMONIUM ZIRCONIUM HYDROXY CITRATE 149564-62-5 176.170
7083 AMMONIUM ZIRCONIUM HYDROXY LACTATE 149564-63-6 176.170
5084 AMMONIUM ZIRCONYL CARBONATE 32535-84-5 176.170
5085 AMYL ACETATE 628-63-7 175.105
5086 AMYL DECYL PHTHALATE 7493-81-4 177.2600
5544 AMYL FUMARATE 20314-74-3 175.105
175.300
176.170
5393 AMYL MALEATE 10099-71-5 175.300
176.170
5087 AMYLOSE 9005-82-7 176.180
5088 AMYLPHENOL, P-TERT- 80-46-6 175.300
177.2410
178.1010
5089 ANHYDROENNEAHEPTITOL 4744-47-2 175.105
5090 ANHYDROGALACTOSE 1319-78-4
5091 ANILINE 62-53-3 177.2600
8278 ANIMAL FAT 92113-40-1 166.110
175.105
8279 ANIMAL FAT, HYDROGENATED 68953-18-4 175.105
7625 ANIMAL OIL FATTY ACID AMIDES 977139-08-4 175.320
178.3860
5092 9,10-ANTHRAQUINONE 84-65-1 176.170
5093 ANTIMONY OXIDE 1327-33-9 175.105
5094 ARACHIDYL-BEHENYL AMIDE 1320-64-5 177.1210
178.3860
5095 ASBESTOS 1332-21-4 175.105
177.2410
177.2420
177.2600
5097 ASPHALT, NAPHTHENIC 12001-33-1 175.105
5098 ASPHALT, PARAFFINIC 977079-20-1 175.105
5099 AZELAIC ACID 123-99-9 175.105
175.300
175.320
177.1200
177.1390
177.1500
177.1630
5100 AZO-BIS-ISOBUTYRONITRILE 78-67-1 175.105
176.170
177.2420
5101 BALATA RUBBER 9005-99-6 175.105
177.1210
5102 BARIUM ACETATE 543-80-6 175.105
5103 BARIUM HYDROXIDE 17194-00-2 177.2410
5104 BARIUM METABORATE 13701-59-2 176.180
5105 BARIUM PEROXIDE 1304-29-6 175.105
5106 BARIUM SULFATE 7727-43-7 175.105
176.170
177.2600
178.3297
7508 BEECHNUT FATTY ACIDS 977176-46-7 175.300
5107 BEECHNUT OIL 8015-74-5 175.300
5108 BEHENAMIDE 3061-75-4 177.1200
5501 BENTONITE, MODIFIED WITH DIMETHYLDIOCTADECYLAMMONIUM ION 977059-10-1 176.170
178.3297
5109 1,3-BENZENEDIAMINE 108-45-2 177.2280
177.2550
177.2800
5148 1,4-BENZENEDICARBOXYLIC ACID, BIS(2-(1,1-DIMETHYLETHYL)-6-((3-(1,1-DIMETHYLETHYL)-2-HYDROXY-5-METHYLPHENYL)METHYL)-4-METHYLPHENYL)ESTER 57569-40-1 175.105
178.2010
7153 1,4-BENZENEDICARBOXYLIC ACID, POLYMER WITH 1,4-BUTANEDIOL, (E)-2-BUTENEDIOIC ACID, 1,2-ETHANEDIOL, ETHYL 2-PROPENOATE, HEXANEDIOIC ACID AND 2-PROPENOIC ACID, GRAFT 175419-23-5 177.1500
8281 1,3,5-BENZENETRICARBONYL TRICHLORIDE 4422-95-1 177.2550
5110 BENZETHONIUM CHLORIDE 121-54-0 175.105
5111 1,2-BENZISOTHIAZOLIN-3-ONE 2634-33-5 175.105
176.170
176.180
176.300
177.2600
5112 BENZOFURAN 271-89-6
7509 BENZOGUANAMINE 91-76-9 175.105
175.300
5113 1,4-BENZOQUINONE 106-51-4 177.2420
5114 BENZOQUINONE DIOXIME 105-11-3 177.2600
5115 2-BENZOTHIAZOLYL DIETHYLDITHIOCARBAMATE 95-30-7 177.2600
5715 BENZOTRIAZOLE 95-14-7 178.3910
7138 P-BENZOXYPHENOL 2444-19-1 175.105
8282 BENZOYL CHLORIDE 98-88-4 177.1556
8283 BENZOYL CHLORIDE-3,4-DICARBOXYLIC ANHYDRIDE 1204-28-0 177.2800
5116 BENZYLBIS(HYDROGENATED TALLOW)METHYLAMMONIUM HECTORITE-BIS(HYDROGENATED TALLOW)DIMETHYLAMMONIUM HECTORITE COMPOUND 121888-67-3 175.300
5117 BENZYL BROMOACETATE 5437-45-6 175.105
5306 ORTHO-BENZYL-PARA-CHLOROPHENOL 120-32-1 178.1010
5118 BENZYL(HYDROGENATED TALLOW)DIMETHYLAMMONIUM BENTONITE 71011-24-0 175.300
5119 BENZYL(HYDROGENATED TALLOW)DIMETHYLAMMONIUM BENTONITE-SODIUM STEARATE COMPOUND 121888-68-4 175.300
5120 BENZYLTRIMETHYLAMMONIUM CHLORIDE 56-93-9 177.2420
5362 BICYCLO-(2.2.1)HEPT-2-ENE-6-METHYLACRYLATE 95-39-6 175.105
176.170
176.180
8434 BIPHENYL-2,4-DI-TERT-BUTYL-5-METHYLPHENOL-PHOSPHORUS TRICHLORIDE EACTION PRODUCTS 178358-58-2 178.2010
5122 2-BIPHENYLYL DIPHENYL PHOSPHATE 132-29-6 175.105
5131 BIS(BETA-CARBOBUTOXYETHYL) TIN BIS(ISOOCTYLMERCAOTOACETATE) 63397-60-4 178.2650
5127 BIS(BENZOATE-O)(2-PROPANOLATO)ALUMINUM 105442-85-1 175.105
5146 BIS(HYDROGENATED TALLOW ALKYL)AMINE 61789-79-5 178.3910
8284 N,N'-BIS(3-AMINOPROPYL)ETHYLENEDIAMINE 10563-26-5 176.180
177.2550
7126 1,4-BIS(2,4,6-TRIMETHYLPHENYL)AMINO)-9,10-ANTHRACENEDIONE 116-75-6 178.3297
8082 1,3-BIS(2-HYDROXYETHOXY)BENZENE 102-40-9 177.1345
8084 1,3-BIS(ISOCYANATOMETHYL)BENZENE, TRIMETHYLOL PROPANE ADDUCT 38639-88-2 177.1390
177.1680
5128 1,3-BIS(2-BENZOTHIAZOLYLMERCAPTOMETHYL) UREA 95-35-2 175.105
177.2600
7154 3,9-BIS(2,4-BIS(1-METHYL-1-PHENYLETHYL)PHENOXY)-2,4,8,10-TETRAOXA-3,9-DIPHOPHASPIRO(5,5)UNDECANE 154862-43-8 178.2010

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