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U.S. Department of Health and Human Services

GRAS Notices

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The inventory of GRAS notices provides information about GRAS notices filed within each year since 1998, when FDA received its first GRAS notice. Once FDA has responded to a GRAS notice, the text of FDA's response will also be available as part of the record for that notice. We will update this information approximately monthly. More information about this inventory is available on the GRAS Notice Inventory Introduction page.


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Records Found: 603 Show All Page 1 of 13
GRN No.
(sorted Z-A)
Substance Date of closure FDA's Letter
603 Preparation containing the bacterial monophages, BP-63 and BP-12, specific to Salmonella Pending
602 N-acetyl-D-neuraminic acid Pending
601 Bacillus coagulans SBC37-01 spore preparation Pending
600 Hydroxytyrosol Pending
599 Citrus fiber Pending
598 Thermolysin enzyme preparation derived from Geobacillus stearothermophilus Pending
597 Bacillus coagulans SNZ1969 spores preparation Pending
596 Breadfruit flour Pending
595 gamma-aminobutyric acid Pending
594 α-amylase from Geobacillus stearothermophilus produced in Bacillus licheniformis Pending
593 Colicin Pending
592 β-glucanase from Bacillus subtilis Pending
591 Streptococcus salivarius K12 Pending
590 Pyrroloquinoline quinone Pending
589 Xylanase from Aspergillus niger Sep 17, 2015 FDA has no questions
588 Zeaxanthin from Capsicum annum (paprika) Pending
587 Acetolate decaroxylase from Bacillus brevis produced in Bacillus licheniformis Sep 8, 2015 FDA has no questions
586 Taurine Pending
585 1-methylcyclopropene Pending
584 Cellulase from Penicillium funiculosum Pending
583 Esterified propoxylated glycerol Pending
582 Inulin from Agave tequilana Pending
581 Pea protein Pending
580 Haematococcus pluvialis extract containing astaxanthin esters Pending
579 Lactase from Bifidobacterium bifidum produced in Bacillus subtilis Pending
578 Natamycin Pending
577 Salts from dried mineral water (65% NaCl) Pending
576 Oligofructose and inulin Pending
575 Oat protein Sep 17, 2015 FDA has no questions
574 Phospholipase C from Pseudomonas fluorescens Jul 23, 2015 FDA has no questions
573 Calcium disodium ethylenediaminetetraacetate (EDTA) Oct 15, 2015 FDA has no questions
572 Lactase from Bifidobacterium bifidum produced in Bacillus licheniformis Aug 25, 2015 FDA has no questions
571 2’-Fucosyllactose Pending
570 Magnesium lactate Pending
569 Galacto-oligosaccharides (GOS) Pending
568 Apoaequorin Pending
567 Xylanase from Trichoderma reesei May 7, 2015 FDA has no questions
566 Mannanase from Trichoderma reesei May 20, 2015 FDA has no questions
565 Fucoidan from Undaria pinnatifida Jul 2, 2015 FDA has no questions
564 Protease from Bacillus licheniformis Jul 7, 2015 FDA has no questions
563 Protease from Fusarium venenatum Jul 8, 2015 FDA has no questions
562 Bacillus subtilis Apr 2, 2015 At the notifier's request, FDA ceased to evaluate this notice
561 Bacillus pumilus Apr 2, 2015 At the notifier's request, FDA ceased to evaluate the notice
560 Bacillus licheniformis Apr 2, 2015 At the notifier's request, FDA ceased to evaluate the notice
559 Bacillus coagulans Apr 2, 2015 At the notifier's request, FDA ceased to evaluate the notice
558 Pectin esterase from Aspergillus tubingensis expressed in Trichoderma reesei Jul 23, 2015 FDA has no questions
557 Polygalacturonase from Aspergillus tubingensis expressed in Trichoderma reesei Jul 23, 2015 FDA has no questions
556 Siraitia grosvenorii Swingle (Luo Han Guo) fruit extract Jun 17, 2015 FDA has no questions
555 High purity steviol glycosides (minimum purity 95%) consisting primarily of rebaudioside A. Apr 20, 2015 FDA has no questions
554 Synthetic amorphous silica May 14, 2015 FDA has no questions

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GRN No.
(sorted Z-A)
Substance Date of closure FDA's Letter
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