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U.S. Department of Health and Human Services

GRAS Notices

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The inventory of GRAS notices provides information about GRAS notices filed within each year since 1998, when FDA received its first GRAS notice. Once FDA has responded to a GRAS notice, the text of FDA's response will also be available as part of the record for that notice. We will update this information approximately monthly. More information about this inventory is available on the GRAS Notice Inventory Introduction page.


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Records Found: 517 Show All Page 1 of 11
GRN No.
(sorted Z-A)
Substance Date of closure FDA's Letter
517 Natamycin Pending
516 Steviol glycosides with rebaudioside A and stevioside as the principal components Pending
515 D-beta-hydroxybutyrate ester Pending
514 Sucrose fatty acid esters Pending
513 Dried biomass of Euglena gracilis containing beta-1,3-glucan from Euglena gracilis Pending
512 High purity Rebaudioside M Pending
511 Citric acid esters of mono- and diglycerides Pending
510 Acid lactase from Aspergillus oryzae expressed in Aspergillus niger Pending
509 Glucose oxidase enzyme preparation derived from Penicillium chrysogenum Pending
508 Salts from dried mineral water (65% NaCl) Pending
507 Amylomaltase enzyme preparation from Bacillus amyloliquefaciens carrying an amylomaltase gene from Thermus thermophiles Pending
506 Sacha inchi oil, a vegetable oil derived from Plukenetia volubilis. Pending
505 Phosphodiesterase I enzyme preparation from Leptographium procerum Pending
504 Concentrated milk proteins Pending
503 Tamarind seed polysaccharide Pending
502 Lactobacillus acidophilus La-14 Pending
501 L-theanine (chemically synthesized) Pending
500 Hydroethanolic extract of Caralluma fimbriata Pending
499 Magnesium L-threonate hydrate Pending
498 Psicose Pending
497 Polyphenols from the fruit of Litchi chinensis Sonn. and from leaves of Camellia sinensis (L.) Sinensis Pending
496 Aqueous extract of Brassica oleracea var. italica Plenck seeds. Pending
495 Galacto-oligosaccharides May 30, 2014 FDA has no questions
494 Fatty acid ethyl ester from anchovy or menhaden oil, standardized to approximately 50 percent palmitoleic acid Pending
493 High purity steviol glycosides (minimum purity 95%) May 30, 2014 FDA has no questions
492 Phytosterols and phytosterol esters Pending
491 Rooster combs extract Pending
490 Phospholipase A2 enzyme preparation from Trichoderma reesei Pending
489 Galacto-oligosaccharides May 22, 2014 FDA has no questions
488 Benzalkonium chloride Pending
487 Dried citrus pulp Pending
486 Oil from the seeds of Buglossoides arvensis Pending
485 Beta-galactosidase enzyme preparation Apr 15, 2014 FDA has no questions
484 Galacto-oligosaccharides May 8, 2014 FDA has no questions
483 Aqueous extract of Emblica officinalis Mar 17, 2014 FDA has no questions
482 Beta-glucanase and xylanase enzyme preparation from Disporotrichum dimorphosporum Pending
481 Meso-zeaxanthin Apr 11, 2014 FDA has no questions
480 Dried aqueous extract derived from white kidney bean (Phaseolus vulgaris) May 30, 2014 FDA has no questions
479 Beta-glucanase, cellulase, and xylanase enzyme preparation from Talaromyces emersonii Mar 7, 2014 FDA has no questions
478 Rice hull fiber Pending
477 Long-chain inulin Mar 4, 2014 FDA has no questions
476 Asparaginase enzyme preparation produced by genetically modified Bacillus subtilis Feb 3, 2014 FDA has no questions
475 Citrus fruit extract May 8, 2014 FDA has no questions
474 Piperine derived from the fruits of Piper nigrum L (black pepper) or P. longum (long pepper) Oct 30, 2013 At the notifier's request, FDA ceased to evaluate the notice
473 Purified steviol glycosides with rebaudioside X as the principal component Dec 17, 2013 FDA has no questions
472 Xylanase enzyme preparation derived from Bacillus licheniformis carrying a gene encoding a modified xylanase from B. licheniformis Jan 10, 2014 FDA has no questions
471 Annatto seed extract May 13, 2014 FDA has no questions
470 Ethyl cellulose Dec 16, 2013 FDA has no questions
469 Chlorella protothecoides strain S106 flour with 40-70% lipid (algal flour) Jun 7, 2013 FDA has no questions
468 Preparation containing the bacterial monophages, Fo1a and S16, specific to Salmonella Dec 23, 2013 FDA has no questions

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GRN No.
(sorted Z-A)
Substance Date of closure FDA's Letter
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