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U.S. Department of Health and Human Services

GRAS Notices

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The inventory of GRAS notices provides information about GRAS notices filed within each year since 1998, when FDA received its first GRAS notice. Once FDA has responded to a GRAS notice, the text of FDA's response will also be available as part of the record for that notice. We will update this information approximately monthly. More information about this inventory is available on the GRAS Notice Inventory Introduction page.


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  • Select the specific GRN number below to view additional details about any GRAS Notice.
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Records Found: 637 Show All Page 1 of 13
GRN No.
(sorted Z-A)
Substance Date of closure FDA's Letter
637 Phosphatidylserine derived soy lecithin Pending
636 Phosphatidylserine derived from sunflower Pending
635 Nicotinamide riboside chloride Pending
634 Calcium chloride Pending
633 Whey protein Pending
632 Rebaudioside A from Yarrowia lipolytica Pending
631 Triacylglycerol lipase from Fusarium oxysporum produced in Trichoderma reesei Pending
630 Preparation containing the bacterial monophages, Fo1a and S16, specific to Salmonella Pending
629 Siraitia grosvenorii Swingle (Luo Han Guo) fruit extract Pending
628 endo-1,4-beta-xylanase from Trichoderma reesei Pending
627 Siraitia grosvenorii Swingle (Luo Han Guo) fruit juice concentrate Pending
626 Steviol glycosides produced in Saccharomyces cerevisiae Pending
625 Pyrroloquinoline quinone disodium salt Pending
624 D-allulose 3-epimerase from Arthrobacter globiformis M30 produced in Escherichia coli Pending
623 Fructooligosaccharides Pending
622 Emulsified fish oil Pending
621 Emulsified algal oil Pending
620 Galacto-oligosaccharides Pending
619 Purified steviol glycosides Pending
618 Purified seawater Pending
617 α-amylase from Cytophaga sp. produced in Bacillus licheniformis Pending
616 Acetylated high amylose corn starch (85% amylose) Pending
615 High amylose corn starch (68% amylose) Pending
614 Chromium polynicotinate Pending
613 Apple peel powder Mar 8, 2016 AT the notifier's request, FDA ceased to evaluate this notice
612 Fractionated whey protein isolate containing cow’s milk derived lactoferrin, lactoperoxidase, and transforming growth factor β2 Pending
611 Fractionated whey protein isolate containing cow’s milk derived lactoferrin, lactoperoxidase, and transforming growth factor β2 Pending
610 Isomaltodextrin Pending
609 Rice protein Pending
608 Pea protein Pending
607 Glucosylated steviol glycosides (minimum purity 80%) Pending
606 Vinyl acetate-vinyl laurate copolymers Pending
605 Fructo-oligosaccharides Pending
604 Baker's Yeast (Saccharomyces cerevisiae) expressing asparaginase II Pending
603 Preparation containing the bacterial monophages, BP-63 and BP-12, specific to Salmonella Pending
602 N-acetyl-D-neuraminic acid Feb 1, 2016 FDA has no questions
601 Bacillus coagulans SBC37-01 spore preparation Pending
600 Hydroxytyrosol Pending
599 Citrus fiber Feb 17, 2016 FDA has no questions
598 Thermolysin enzyme preparation derived from Geobacillus stearothermophilus Pending
597 Bacillus coagulans SNZ1969 spores preparation Feb 29, 2016 FDA has no questions
596 Breadfruit flour Feb 21, 2016 FDA has no questions
595 gamma-aminobutyric acid Nov 10, 2015 At the notifier's request, FDA ceased to evaluate this notice
594 α-amylase from Geobacillus stearothermophilus produced in Bacillus licheniformis Dec 18, 2015 FDA has no questions
593 Colicin Dec 9, 2015 FDA has no questions
592 β-glucanase from Bacillus subtilis Oct 7, 2015 FDA has no questions
591 Streptococcus salivarius K12 Jan 25, 2016 FDA has no questions
590 Pyrroloquinoline quinone Jan 18, 2016 At the notifier's request, FDA ceased to evaluate this notice
589 Xylanase from Aspergillus niger Sep 17, 2015 FDA has no questions
588 Zeaxanthin from Capsicum annum (paprika) Feb 29, 2016 FDA has no questions

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GRN No.
(sorted Z-A)
Substance Date of closure FDA's Letter
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