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U.S. Department of Health and Human Services

GRAS Notices

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The inventory of GRAS notices provides information about GRAS notices filed within each year since 1998, when FDA received its first GRAS notice. Once FDA has responded to a GRAS notice, the text of FDA's response will also be available as part of the record for that notice. We will update this information approximately monthly. More information about this inventory is available on the GRAS Notice Inventory Introduction page.


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Records Found: 498 Show All Page 1 of 10
GRN No.
(sorted Z-A)
Substance Date of closure FDA's Letter
498 Psicose Pending
497 Polyphenols from extracts of Litchi chinensis Sonn. and Camellia sinensis (L.) Sinensis Pending
496 Aqueous extract of Brassica oleracea var. italica Plenck seeds. Pending
495 Galacto-oligosaccharides Pending
494 Fatty acid ethyl ester from anchovy or menhaden oil, standardized to approximately 50 percent palmitoleic acid Pending
493 High purity steviol glycosides (minimum purity 95%) Pending
492 Phytosterols and phytosterol esters Pending
491 Rooster combs extract Pending
490 Phospholipase A2 enzyme preparation from Trichoderma reesei Pending
489 Galacto-oligosaccharides Pending
488 Benzalkonium chloride Pending
487 Dried citrus pulp Pending
486 Oil from the seeds of Buglossoides arvensis Pending
485 Beta-galactosidase enzyme preparation Pending
484 Galacto-oligosaccharides Pending
483 Aqueous extract of Emblica officinalis Pending
482 Beta-glucanase and xylanase enzyme preparation from Disporotrichum dimorphosporum Pending
481 Meso-zeaxanthin Pending
480 Dried aqueous extract derived from white kidney bean (Phaseolus vulgaris) Pending
479 Beta-glucanase, cellulase, and xylanase enzyme preparation from Talaromyces emersonii Pending
478 Rice hull fiber Pending
477 Long-chain inulin Pending
476 Asparaginase enzyme preparation produced by genetically modified Bacillus subtilis Pending
475 Citrus fruit extract Pending
474 Piperine derived from the fruits of Piper nigrum L (black pepper) or P. longum (long pepper) Oct 30, 2013 At notifier's request, FDA ceased to evaluate the notice
473 Purified steviol glycosides with rebaudioside X as the principal component Dec 17, 2013 FDA has no questions
472 Xylanase enzyme preparation derived from Bacillus licheniformis carrying a gene encoding a modified xylanase from B. licheniformis Jan 10, 2014 FDA has no questions
471 Annatto seed extract Pending
470 Ethyl cellulose Dec 16, 2013 FDA has no questions
469 Chlorella protothecoides strain S106 flour with 40-70% lipid (algal flour) Jun 7, 2013 FDA has no questions
468 Preparation containing the bacterial monophages, Fo1a and S16, specific to Salmonella Pending
467 Rebaudioside A purified from the leaves of Stevia rebaudiana (Bertoni) Bertoni Nov 25, 2013 FDA has no questions
466 Polyglycerol polyricinoleic acid Sep 25, 2013 FDA has no questions
465 Cow's milk-derived lactoferrin Pending
464 Cow's milk-derived lactoferrin Pending
463 Lactobacillus acidophilus strain NP 28, Lactobacillus acidophilus strain NP51, Lactobacillus subsp. lactis strain NP7, and Pediococcus acidilactici strain NP3 Pending
462 Lipase enzyme preparation from modified Pseudomonas fluorescens Biovar I Jun 6, 2013 FDA has no questions
461 Rebaudioside A purified from the leaves of Stevia rebaudiana (Bertoni) Bertoni (rebaudioside A) Aug 14, 2013 FDA has no questions
460 Curcuminoids purified from turmeric (Curcuma longa L.) Aug 23, 2013 FDA has no questions; some uses may require a color additive listing
459 Olive pulp extract Apr 2, 2013 At notifier's request, FDA ceased to evaluate the notice
458 Xylooligosaccharides Aug 23, 2013 FDA has no questions
457 Bacteriodes xylanisolvens strain DSM 23964 Dec 16, 2013 FDA has no questions
456 Rebaudioside D purified from the leaves of Stevia rebaudiana (Bertoni) Bertoni (rebaudioside D) Jul 1, 2013 FDA has no questions
455 Bifidobacterium breve M-16V Sep 30, 2013 FDA has no questions
454 Bifidobacterium breve M-16V Sep 27, 2013 FDA has no questions
453 Bifidobacterium breve M-16V Sep 27, 2013 FDA has no questions
452 Enzyme-modified steviol glycosides Jul 1, 2013 FDA has no questions
451 Calcium ascorbate with added threonate Aug 5, 2013 FDA has no questions
450 Chlorella protothecoides S106 flour with 40-70% lipid Apr 19, 2013 At notifier's request, FDA ceased to evaluate the notice
449 Medium chain triglycerides Pending

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GRN No.
(sorted Z-A)
Substance Date of closure FDA's Letter
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