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U.S. Department of Health and Human Services

GRAS Notices

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The inventory of GRAS notices provides information about GRAS notices filed within each year since 1998, when FDA received its first GRAS notice. Once FDA has responded to a GRAS notice, the text of FDA's response will also be available as part of the record for that notice. We will update this information approximately monthly. More information about this inventory is available on the GRAS Notice Inventory Introduction page.


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Records Found: 579 Show All Page 1 of 12
GRN No.
(sorted Z-A)
Substance Date of closure FDA's Letter
579 Lactase from Bifidobacterium bifidum produced in Bacillus subtilis Pending
578 Natamycin Pending
577 Salts from dried mineral water (65% NaCl) Pending
576 Oligofructose and inulin Pending
575 Oat protein Pending
574 Phospholipase C from Pseudomonas fluorescens Pending
573 Calcium disodium ethylenediaminetetraacetate (EDTA) Pending
572 Lactase from Bifidobacterium bifidum produced in Bacillus licheniformis Pending
571 2’-Fucosyllactose Pending
570 Magnesium lactate Pending
569 Galacto-oligosaccharides (GOS) Pending
568 Apoaequorin Pending
567 Xylanase from Trichoderma reesei May 7, 2015 FDA has no questions
566 Mannanase from Trichoderma reesei May 20, 2015 FDA has no questions
565 Fucoidan from Undaria pinnatifida Pending
564 Protease from Bacillus licheniformis Pending
563 Protease from Fusarium venenatum Pending
562 Bacillus subtilis Pending
561 Bacillus pumilus Pending
560 Bacillus licheniformis Pending
559 Bacillus coagulans Pending
558 Pectin esterase from Aspergillus tubingensis expressed in Trichoderma reesei Pending
557 Polygalacturonase from Aspergillus tubingensis expressed in Trichoderma reesei Pending
556 Siraitia grosvenorii Swingle (Luo Han Guo) fruit extract Pending
555 High purity steviol glycosides (minimum purity 95%) consisting primarily of rebaudioside A. Apr 20, 2015 FDA has no questions
554 Synthetic amorphous silica Pending
553 Algal oil (40% docosahexaenoic acid) derived from Schizochytrium sp. Pending
552 Succinic acid May 13, 2015 FDA has no questions
551 Aspartic protease derived from the flowers of Cynera cardunculus L. Mar 26, 2015 FDA has no questions
550 Meso-zeaxanthin Mar 27, 2015 FDA has no questions
549 Sodium salts of fatty acids from Mortierella alpina oil Pending
548 High purity rebaudioside D Apr 20, 2015 FDA has no questions
547 Lacto-N-neotetraose Pending
546 2'-O-fucosyllactose Pending
545 Phosphatidylserine derived from sunflower Pending
544 β-glucans from oat bran Pending
543 Lutein esters Mar 16, 2015 FDA has no questions
542 Lutein Mar 16, 2015 FDA has no questions
541 Insoluble fiber from citrus peel Pending
540 Soybean leghemoglobin from Pichia pastoris Pending
539 Fish oil Pending
538 Potassium-rich extract from Saccharum officinarum L. (sugarcane) Apr 8, 2015 FDA has no questions
537 Short-chain fructo-oligosaccharides Feb 5, 2015 FDA has no questions
536 High purity rebaudioside C Feb 10, 2015 FDA has no questions
535 Beta-glucanase from Streptomyces violaceoruber Pending
534 Hydrogenated lecithin from soy Dec 22, 2014 FDA has no questions
533 Lecithin from canola Mar 18, 2015 FDA has no questions
532 Iron complex of tartaric acid Feb 6, 2015 FDA has no questions
531 Lactobacillus fermentum CECT5716 Mar 20, 2015 FDA has no questions
530 Extract of Apocynum venetum leaves Dec 2, 2014 At the notifier's request, FDA ceased to evaluate the notice

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GRN No.
(sorted Z-A)
Substance Date of closure FDA's Letter
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