Scientific Publications by FDA Staff

Recent Scientific Publications: Toxicological Research

• Methods Mol Biol 2013;1002:93-103
  Phosphopeptide enrichment using offline titanium dioxide columns for phosphoproteomics.
• Toxicology 2013 Feb 8;304:109-19
  6-OHDA-induced apoptosis and mitochondrial dysfunction are mediated by early modulation of intracellular signals and interaction of Nrf2 and NF-kappaB factors.
• RNA 2013 Apr;19(4):479-89
  Incorporating the human gene annotations in different databases significantly improved transcriptomic and genetic analyses.
• Pers Med 2013 Mar;10(2):191-9
  KRAS mutant tumor subpopulations can subvert durable responses to personalized cancer treatments
• J Am Assoc Lab Anim Sci 2013 Mar;52(2):130-41
  The estrogenic content of rodent diets, bedding, cages, and water bottles and its effect on bisphenol a studies.
• Kidney Int 2013 Mar;7(1):171-9
  Association of IL28B genotypes with metabolic profiles and viral clearance rate in chronic hepatitis C patients
• Antimicrob Agents Chemother 2013 Apr 15 [Epub ahead of print]
  Emergence of New Delhi Metallo-beta-Lactamase (NDM-1) encoding gene in Clinical Escherichia coli Isolates Recovered from Companion Animals in the United States.
• Pers Med 2013 Mar;10(2):149-61
  Metabolomics as a tool for personalizing medicine: 2012 update
• BMC Genomics 2013 Mar 5;14:147
  Comparison of the global gene expression of choroid plexus and meninges and associated vasculature under control conditions and after pronounced hyperthermia or amphetamine toxicity.
• BMC Microbiol 2013 Mar 1;13:50
  Comparative transcription analysis and toxin production of two fluoroquinolone-resistant mutants of Clostridium perfringens.
• Expert Opin Drug Metab Toxicol 2013 Apr 9 [Epub ahead of print]
  Role of microRNAs in the regulation of drug metabolism and disposition genes in diabetes and liver disease.
• Toxicol Appl Pharmacol 2013 Apr 5 [Epub ahead of print]
  Prediction and Evaluation of Route Dependent Dosimetry of BPA in Rats at Different Life Stages Using a Physiologically Based Pharmacokinetic Model.
• Toxicol Ind Health 2013 Apr 3 [Epub ahead of print]
  UVA photoirradiation of benzo[a]pyrene metabolites: induction of cytotoxicity, reactive oxygen species, and lipid peroxidation.
• Biomark Med 2013 Apr;7(2):307-15
  Hopes and challenges in using miRNAs as translational biomarkers for drug-induced liver injury.
• Neurosci Lett 2013 Feb 22;535:24-9
  Bone marrow-derived microglia-based neurturin delivery protects against dopaminergic neurodegeneration in a mouse model of Parkinson's disease.
• Toxicol Sci 2013 Mar;132(1):177-95
  An animal model of marginal iodine deficiency during development: the thyroid axis and neurodevelopmental outcome.
• BMC Med Res Methodol 2013 Feb 20;13:25
  Assessment of reproducibility of cancer survival risk predictions across medical centers.
• Toxicol Sci 2013 Mar;132(1):53-63
  Molecular mechanisms of fibrosis-associated promotion of liver carcinogenesis.
• Pharmgenomics Pers Med 2013;6:9-17
  GSTM1 copy number and promoter haplotype as predictors for risk of recurrence and/or second primary tumor in patients with head and neck cancer.
• Sci China Life Sci 2013 Mar;56(3):292
  Erratum to: Studies on abacavir-induced hypersensitivity reaction: a successful example of translation of pharmacogenetics to personalized medicine.
• Clin Pharmacol Ther 2013 Mar;93(3):267-74
  Multiple dosing of ephedra-free dietary supplements: hemodynamic, electrocardiographic, and bacterial contamination effects.
• Toxicol Sci 2013 Mar 20 [Epub ahead of print]
  'Non-decolorized' Qualifier is a Misnomer for the Aloe vera Whole Leaf Extract Test Material.
• PLoS One 2013;8(3):e59224
  Meta-analysis of pulsed-field gel electrophoresis fingerprints based on a constructed salmonella database.
• ALTEX 2013;30(1):51-6
  Perspectives on validation of high-throughput assays supporting 21st century toxicity testing.
• Neurosci Lett 2013 Mar 7 [Epub ahead of print]
  Chronic exposure to rotenone, a dopaminergic toxin, results in peripheral neuropathy associated with dopaminergic damage.