Scientific Publications by FDA Staff
Photochem Photobiol 1981 Dec;34(6):741-3
Ultraviolet radiation induced changes in macrophage activity.
Schuller GB, Hellman KB
The effect of ultraviolet (UV) radiation on macrophage activity was examined. Thioglycollate-stimulated peritoneal exudate cells were collected from adult C57BL/6 mice. Ninety-five per cent of the cells adhering to plastic petri dishes were macrophages as determined by the presence of a non-specific esterase. Adherent cells were exposed to UV radiation of 0.5-13.2 J/m2. Viability and phagocytosis were measured at 0, 24, 48, 72 and 96 h after exposure. A statistically significant UV exposure-dependent decrease in macrophage viability and phagocytic capacity was observed. Macrophage viability and phagocytosis also decreased as a function of time after exposure to UV radiation.
|Category: Journal Article|
|PubMed ID: #7312958||DOI: 10.1111/j.1751-1097.1981.tb09072.x|
|Includes FDA Authors from Scientific Area(s): Medical Devices|
|Entry Created: 2012-12-09|