Scientific Publications by FDA Staff
Rapid Commun Mass Spectrom 1996;10(6):715-20
Characterization of nitrosation products in cosmetics raw materials by liquid chromatography/mass spectrometry techniques.
Volmer DA, Lay JO, Billedeau M, Vollmer DL
Characterization of nitrosation products in cosmetics raw material samples has been accomplished by three liquid chromatography/mass spectrometry (LC/MS) techniques. Two of the techniques involved conventional methodologies of LC/MS and LC/tandem mass spectrometry, both of which can be used to detect and identify products formed under extreme-nitrosation conditions. The third technique utilized an on-line coupling of a photolysis reactor with the LC/MS, and it may be used as a rapid and specific means of screening for the presence of known and unknown N-nitrosamines, which may be carcinogenic.
|Category: Journal Article|
|PubMed ID: #8624419||DOI: 10.1002/(SICI)1097-0231(199604)10:6<715::AID-RCM542>3.0.CO;2-K|
|Includes FDA Authors from Scientific Area(s): Toxicological Research|
|Entry Created: 2012-12-25|