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Emerg Infect Dis 2012 Aug;18(8):e1

Infectious disease transmission during organ and tissue transplantation.

Greenwald MA, Kuehnert MJ, Fishman JA

Abstract

Infectious disease transmission through organ and tissue transplantation has been associated with severe complications in recipients. Determination of donor-derived infectious risk associated with organ and tissue transplantation is challenging and limited by availability and performance characteristics of current donor epidemiologic screening (e.g., questionnaire) and laboratory testing tools. Common methods and standards for evaluating potential donors of organs and tissues are needed to facilitate effective data collection for assessing the risk for infectious disease transmission. Research programs can use advanced microbiological technologies to define infectious risks posed by pathogens that are known to be transplant transmissible and provide insights into transmission potential of emerging infectious diseases for which transmission characteristics are unknown. Key research needs are explored. Stakeholder collaboration for surveillance and research infrastructure is required to enhance transplant safety.


Category: Journal Article
PubMed ID: #22840823 DOI: 10.3201/eid1808.120277
PubMed Central ID: #PMC3414044
Includes FDA Authors from Scientific Area(s): Biologics
Entry Created: 2013-01-15
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