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J Nat Prod 2015 Jan 14 [Epub ahead of print]

Sesquiterpenoid Tropolone Glycosides from Liriosma ovata.

Ma J, Pawar RS, Grundel E, Mazzola EP, Ridge CD, Masaoka T, Le Grice SF, Wilson J, Beutler JA, Krynitsky AJ

Abstract

Two new sesquiterpenoid tropolone glycosides, liriosmasides A (1) and B (2), along with two known compounds, secoxyloganin and oplopanpheside C, were isolated from a methanol extract of the roots of Liriosma ovata. The structures of 1 and 2 were elucidated by spectroscopic methods including 1D and 2D NMR and by high-resolution mass spectrometry involving an ultra-high-performance liquid chromatography-quadrupole-orbital ion trap mass spectrometric (UHPLC-Q-Orbitrap MS) method. Compound 1 showed weak inhibitory activity against HIV RNase H.

Category: Journal Article
PubMed ID: #25587934 DOI: 10.1021/np5006696
Includes FDA Authors from Scientific Area(s): Food
Entry Created: 2015-01-15
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