Scientific Publications by FDA Staff

J AOAC Int 2015 May-Jun;98(3):588-94

Quantitation of chloramphenicol and nitrofuran metabolites in aquaculture products using microwave-assisted derivatization, automated SPE, and LC-MS/MS.

Veach BT, Baker CA, Kibbey JH, Fong A, Broadaway BJ, Drake CP

This paper describes a rapid and robust method utilizing microwave-assisted derivatization, automated SPE, and LC-MS/MS for the quantitation and confirmation of chloramphenicol (CAP) and nitrofuran metabolites in various aquaculture matrixes. The use of equipment presented in this work allowed extractions to be completed on average within 6 h, with quantitation accuracy ranging from 89 to 107% and RSD